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Prospective, high-throughput molecular profiling of human gliomas

Prospective, high-throughput molecular profiling of human gliomas

http://www.wikidata.org/entity/Q41970534

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Structural mutation analysis of PTEN and its genotype-phenotype correlations in endometriosis and cancer Targetable signaling pathway mutations are associated with malignant phenotype in IDH-mutant gliomas.Intraoperative mass spectrometry mapping of an onco-metabolite to guide brain tumor surgery Brain tumor cells in circulation are enriched for mesenchymal gene expression Insulator dysfunction and oncogene activation in IDH mutant gliomas.A computational model incorporating neural stem cell dynamics reproduces glioma incidence across the lifespan in the human population Using the apparent diffusion coefficient to identifying MGMT promoter methylation status early in glioblastoma: importance of analytical method Clinical implementation of integrated whole-genome copy number and mutation profiling for glioblastoma.Phase II trial of continuous low-dose temozolomide for patients with recurrent malignant glioma.Treatment Response Assessment in IDH-Mutant Glioma Patients by Noninvasive 3D Functional Spectroscopic Mapping of 2-Hydroxyglutarate.Molecular pathologic diagnosis of epidermal growth factor receptor.Blockade of transforming growth factor-β signaling enhances oncolytic herpes simplex virus efficacy in patient-derived recurrent glioblastoma models.High levels of c-Met is associated with poor prognosis in glioblastoma.Novel MET/TIE2/VEGFR2 inhibitor altiratinib inhibits tumor growth and invasiveness in bevacizumab-resistant glioblastoma mouse models Molecular Diagnostics of Gliomas Using Next Generation Sequencing of a Glioma-Tailored Gene Panel.Volumetric relationship between 2-hydroxyglutarate and FLAIR hyperintensity has potential implications for radiotherapy planning of mutant IDH glioma patients.Clinical targeted exome-based sequencing in combination with genome-wide copy number profiling: precision medicine analysis of 203 pediatric brain tumors.Retrospective Analysis of Molecular and Immunohistochemical Characterization of 381 Primary Brain Tumors.Patterns of response to crizotinib in recurrent glioblastoma according to ALK and MET molecular profile in two patients.Pharmacodynamics of mutant-IDH1 inhibitors in glioma patients probed by in vivo 3D MRS imaging of 2-hydroxyglutarate.

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Prospective, high-throughput molecular profiling of human gliomas

http://www.wikidata.org/entity/Q41970534

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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name

Prospective, high-throughput molecular profiling of human gliomas

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Prospective, high-throughput molecular profiling of human gliomas

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Prospective, high-throughput molecular profiling of human gliomas

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S11060-012-0938-9

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Journal of Neuro-Oncology

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Prospective, high-throughput molecular profiling of human gliomas

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A John Iafrate

http://www.w3.org/2001/XMLSchema#string

Andrew S Chi

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Charles D Stiles

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Daphne L Wang

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Darrell Borger

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David N Louis

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Dora Dias-Santagata

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Keith L Ligon

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Leif Ellisen

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Patrick Y Wen

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P2860

Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma

Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma

The COSMIC (Catalogue of Somatic Mutations in Cancer) database and website

An integrated genomic analysis of human glioblastoma multiforme

IDH1 and IDH2 mutations in gliomas

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

Molecular genetic analysis of giant cell glioblastomas

Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy.

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s11060-012-0938-9

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89-98

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