Low-affinity transcription factor binding sites shape morphogen responses and enhancer evolution.
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Regulatory Principles Governing Tissue Specificity of Developmental EnhancersBipartite recognition of DNA by TCF/Pangolin is remarkably flexible and contributes to transcriptional responsiveness and tissue specificity of wingless signalingWnt-mediated repression via bipartite DNA recognition by TCF in the Drosophila hematopoietic systemGenome-wide use of high- and low-affinity Tbrain transcription factor binding sites during echinoderm developmentHedgehog signaling establishes precursors for germline stem cell niches by regulating cell adhesion.Evolution of transcription factor function as a mechanism for changing metazoan developmental gene regulatory networksIdentification and Validation of Novel Hedgehog-Responsive Enhancers Predicted by Computational Analysis of Ci/Gli Binding Site DensityIntersecting transcription networks constrain gene regulatory evolutionA systematic, large-scale comparison of transcription factor binding site models.In silico evolution of the Drosophila gap gene regulatory sequence under elevated mutational pressureTo Be Specific or Not: The Critical Relationship Between Hox And TALE Proteins.An ancient yet flexible cis-regulatory architecture allows localized Hedgehog tuning by patched/Ptch1.Syntax compensates for poor binding sites to encode tissue specificity of developmental enhancersMechanisms of Specificity for Hox Factor Activity.Transcriptional regulation of graded Hedgehog signalingMathematical Modeling of Avidity Distribution and Estimating General Binding Properties of Transcription Factors from Genome-Wide Binding Profiles.Mocap: large-scale inference of transcription factor binding sites from chromatin accessibilityStable Binding of the Conserved Transcription Factor Grainy Head to its Target Genes Throughout Drosophila melanogaster Development.The Canonical Notch Signaling Pathway: Structural and Biochemical Insights into Shape, Sugar, and Force.Molecular Evidence for Functional Divergence and Decay of a Transcription Factor Derived from Whole-Genome Duplication in Arabidopsis thaliana.Low affinity binding site clusters confer hox specificity and regulatory robustness.How to tune an enhancer.Evolution of transcriptional enhancers and animal diversity.Spurious transcription factor binding: non-functional or genetically redundant?Nuclear microenvironments modulate transcription from low-affinity enhancers.Natural variation in stochastic photoreceptor specification and color preference in Drosophila.CRNET: An efficient sampling approach to infer functional regulatory networks by integrating large-scale ChIP-seq and time-course RNA-seq data.DNA Occupancy of Polymerizing Transcription Factors: A Chemical Model of the ETS Family Factor Yan.Degenerate Pax2 and Senseless binding motifs improve detection of low-affinity sites required for enhancer specificity.A thousand empirical adaptive landscapes and their navigability.
P2860
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P2860
Low-affinity transcription factor binding sites shape morphogen responses and enhancer evolution.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
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2013年论文
@zh-cn
name
Low-affinity transcription fac ...... ponses and enhancer evolution.
@en
type
label
Low-affinity transcription fac ...... ponses and enhancer evolution.
@en
prefLabel
Low-affinity transcription fac ...... ponses and enhancer evolution.
@en
P2860
P356
P1476
Low-affinity transcription fac ...... ponses and enhancer evolution.
@en
P2093
Andrea I Ramos
Scott Barolo
P2860
P304
P356
10.1098/RSTB.2013.0018
P407
P577
2013-11-11T00:00:00Z