Determination of key residues for catalysis and RNA cleavage specificity: one mutation turns RNase II into a "SUPER-ENZYME".

Determination of key residues for catalysis and RNA cleavage specificity: one mutation turns RNase II into a "SUPER-ENZYME".

Item
http://www.wikidata.org/entity/Q41971543
Initial genome sequencing and analysis of multiple myelomaMechanism of Dis3l2 substrate recognition in the Lin28-let-7 pathwaySubstrate recognition and specificity of double-stranded RNA binding proteins.Selective 2'-hydroxyl acylation analyzed by protection from exoribonuclease.Identification and analysis of the RNA degrading complexes and machinery of Giardia lamblia using an in silico approach.The rnb gene of Synechocystis PCC6803 encodes a RNA hydrolase displaying RNase II and not RNase R enzymatic propertiesThe RNase R from Campylobacter jejuni has unique features and is involved in the first steps of infection.Modulating the RNA processing and decay by the exosome: altering Rrp44/Dis3 activity and end-productSelective 2'-hydroxyl acylation analyzed by protection from exoribonuclease (RNase-detected SHAPE) for direct analysis of covalent adducts and of nucleotide flexibility in RNAMultiple myeloma-associated hDIS3 mutations cause perturbations in cellular RNA metabolism and suggest hDIS3 PIN domain as a potential drug target.The genetic architecture of multiple myeloma.The critical role of RNA processing and degradation in the control of gene expression.The RNase II/RNB family of exoribonucleases: putting the 'Dis' in disease.RNase R mutants elucidate the catalysis of structured RNA: RNA-binding domains select the RNAs targeted for degradation.Structural analysis of mtEXO mitochondrial RNA degradosome reveals tight coupling of nuclease and helicase components.
P2860

Determination of key residues for catalysis and RNA cleavage specificity: one mutation turns RNase II into a "SUPER-ENZYME".

Item
http://www.wikidata.org/entity/Q41971543
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Determination of key residues ...... Nase II into a "SUPER-ENZYME".
@en
type
label
Determination of key residues ...... Nase II into a "SUPER-ENZYME".
@en
prefLabel
Determination of key residues ...... Nase II into a "SUPER-ENZYME".
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932
P356
P1433
P1476
Determination of key residues ...... Nase II into a "SUPER-ENZYME".
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932