Bmp2 transcription in osteoblast progenitors is regulated by a distant 3' enhancer located 156.3 kilobases from the promoter.
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ARID1a-DNA interactions are required for promoter occupancy by SWI/SNFA nonsynonymous mutation in the transcriptional regulator lbh is associated with cichlid craniofacial adaptation and neural crest cell development.UTX and UTY demonstrate histone demethylase-independent function in mouse embryonic developmentInhibition of microtubule assembly in osteoblasts stimulates bone morphogenetic protein 2 expression and bone formation through transcription factor Gli2Bmp2 and Bmp4 exert opposing effects in hypoxic pulmonary hypertensionFunctional analysis of limb transcriptional enhancers in the mouseShaping skeletal growth by modular regulatory elements in the Bmp5 geneLong bone structure and strength depend on BMP2 from osteoblasts and osteocytes, but not vascular endothelial cells.Repressive BMP2 gene regulatory elements near the BMP2 promoter.Control elements targeting Tgfb3 expression to the palatal epithelium are located intergenically and in introns of the upstream Ift43 geneMutation of Rubie, a novel long non-coding RNA located upstream of Bmp4, causes vestibular malformation in mice.Repression of the soma-specific transcriptome by Polycomb-repressive complex 2 promotes male germ cell development.Tbx2 and Tbx3 induce atrioventricular myocardial development and endocardial cushion formationThe BMP ligand Gdf6 prevents differentiation of coronal suture mesenchyme in early cranial development.An autonomous BMP2 regulatory element in mesenchymal cells.Skeletal trauma generates systemic BMP2 activation that is temporally related to the mobilization of CD73+ cells.Relevance of BAC transgene copy number in mice: transgene copy number variation across multiple transgenic lines and correlations with transgene integrity and expressionIdentification of duplication downstream of BMP2 in a Chinese family with brachydactyly type A2 (BDA2).Multivariate analysis of regulatory SNPs: empowering personal genomics by considering cis-epistasis and heterogeneityRestoration of spermatogenesis and male fertility using an androgen receptor transgene.Genome-scale techniques highlight the epigenome and redefine fundamental principles of gene regulation.The intronic GABRG2 mutation, IVS6+2T->G, associated with childhood absence epilepsy altered subunit mRNA intron splicing, activated nonsense-mediated decay, and produced a stable truncated γ2 subunit.An in vivo map of bone morphogenetic protein 2 post-transcriptional repression in the heartRegenerative effects of transplanted mesenchymal stem cells in fracture healing.The SWI/SNF BAF-A complex is essential for neural crest developmentMesenchymal stem cells expressing insulin-like growth factor-I (MSCIGF) promote fracture healing and restore new bone formation in Irs1 knockout mice: analyses of MSCIGF autocrine and paracrine regenerative effects.Dynamics and cellular localization of Bmp2, Bmp4, and Noggin transcription in the postnatal mouse skeleton.Pitx1 broadly associates with limb enhancers and is enriched on hindlimb cis-regulatory elementsConstructing genomic maps of positive selection in humans: where do we go from here?Turning Bone Morphogenetic Protein 2 (BMP2) on and off in Mesenchymal Cells.Vascular tissues are a primary source of BMP2 expression during bone formation induced by distraction osteogenesisBMP-2 vs. BMP-4 expression and activity in glucocorticoid-arrested MC3T3-E1 osteoblasts: Smad signaling, not alkaline phosphatase activity, predicts rescue of mineralization.BMP2 Regulation of CXCL12 Cellular, Temporal, and Spatial Expression is Essential During Fracture Repair.Duplications involving a conserved regulatory element downstream of BMP2 are associated with brachydactyly type A2.Fate mapping using Cited1-CreERT2 mice demonstrates that the cap mesenchyme contains self-renewing progenitor cells and gives rise exclusively to nephronic epithelia.Hox11 genes are required for regional patterning and integration of muscle, tendon and bone.A novel distal enhancer mediates cytokine induction of mouse RANKl gene expression.Control of BMP gene expression by long-range regulatory elements.Fundamentals of vitamin D hormone-regulated gene expression.Gene regulation during development in the light of topologically associating domains.
P2860
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P2860
Bmp2 transcription in osteoblast progenitors is regulated by a distant 3' enhancer located 156.3 kilobases from the promoter.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Bmp2 transcription in osteobla ...... 3 kilobases from the promoter.
@en
type
label
Bmp2 transcription in osteobla ...... 3 kilobases from the promoter.
@en
prefLabel
Bmp2 transcription in osteobla ...... 3 kilobases from the promoter.
@en
P2093
P2860
P356
P1476
Bmp2 transcription in osteobla ...... 3 kilobases from the promoter.
@en
P2093
Douglas P Mortlock
Karen A McFarland
Kelly J Chandler
Ronald L Chandler
P2860
P304
P356
10.1128/MCB.01609-06
P407
P577
2007-02-05T00:00:00Z