Studies of the membrane topology of the rat erythrocyte H+/lactate cotransporter (MCT1).
about
Cloning and sequencing of four new mammalian monocarboxylate transporter (MCT) homologues confirms the existence of a transporter family with an ancient pastThe role of charged residues in the transmembrane helices of monocarboxylate transporter 1 and its ancillary protein basigin in determining plasma membrane expression and catalytic activityThe proton-linked monocarboxylate transporter (MCT) family: structure, function and regulationMajor facilitator superfamilyCD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expressionIdentification and characterization of a monocarboxylate transporter (MCT1) in pig and human colon: its potential to transport L-lactate as well as butyrateHypoxia, cancer metabolism and the therapeutic benefit of targeting lactate/H(+) symportersBasigin (CD147) is the target for organomercurial inhibition of monocarboxylate transporter isoforms 1 and 4: the ancillary protein for the insensitive MCT2 is EMBIGIN (gp70)MCT1 and its accessory protein CD147 are differentially regulated by TSH in rat thyroid cellsThe inhibition of monocarboxylate transporter 2 (MCT2) by AR-C155858 is modulated by the associated ancillary proteinCloning of the monocarboxylate transporter isoform MCT2 from rat testis provides evidence that expression in tissues is species-specific and may involve post-transcriptional regulationStudies on the DIDS-binding site of monocarboxylate transporter 1 suggest a homology model of the open conformation and a plausible translocation cycleAR-C155858 is a potent inhibitor of monocarboxylate transporters MCT1 and MCT2 that binds to an intracellular site involving transmembrane helices 7-10Identification of monocarboxylate transporter 8 as a specific thyroid hormone transporterMutations in MCT1 cDNA in patients with symptomatic deficiency in lactate transportMonocarboxylate transporter 1 (MCT1) mediates transport of short-chain fatty acids in bovine caecum.Monocarboxylate transporter 1 (MCT1) plays a direct role in short-chain fatty acids absorption in caprine rumen.C6ORF192 forms a unique evolutionary branch among solute carriers (SLC16, SLC17, and SLC18) and is abundantly expressed in several brain regions.Lactate transport in skeletal muscle - role and regulation of the monocarboxylate transporter.Renal localization and regulation by dietary phosphate of the MCT14 orphan transporterRole of monocarboxylate transporters in drug delivery to the brain.Role of plasma membrane transporters in muscle metabolism.The monocarboxylate transporter family--Structure and functional characterization.Monocarboxylate transporters and lactate metabolism in equine athletes: a review.Can lactate serve as an energy substrate for axons in good times and in bad, in sickness and in health?Identification of key binding site residues of MCT1 for AR-C155858 reveals the molecular basis of its isoform selectivity.Bicarbonate, NBCe1, NHE, and carbonic anhydrase activity enhance lactate-H+ transport in bovine corneal endothelium.Urocortin prevents mitochondrial permeability transition in response to reperfusion injury indirectly by reducing oxidative stressHistological characterization of orphan transporter MCT14 (SLC16A14) shows abundant expression in mouse CNS and kidney.Molecular identification and characterization of an essential pyruvate transporter from Trypanosoma brucei.Gem-1 encodes an SLC16 monocarboxylate transporter-related protein that functions in parallel to the gon-2 TRPM channel during gonad development in Caenorhabditis elegans.Transport of carboxylic acids in yeasts.Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer.Red fluorescent protein pH biosensor to detect concentrative nucleoside transportMonocarboxylic acid transport.Monocarboxylate transporter mediated uptake of moxifloxacin on human retinal pigmented epithelium cells.Monocarboxylate transporter MCT1 is a target for immunosuppression.Cytochrome c release from isolated rat liver mitochondria can occur independently of outer-membrane rupture: possible role of contact sitesRegulation of oligodendrocyte development and myelination by glucose and lactateThe loop between helix 4 and helix 5 in the monocarboxylate transporter MCT1 is important for substrate selection and protein stability.
P2860
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P2860
Studies of the membrane topology of the rat erythrocyte H+/lactate cotransporter (MCT1).
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Studies of the membrane topology of the rat erythrocyte H+/lactate cotransporter (MCT1).
@en
type
label
Studies of the membrane topology of the rat erythrocyte H+/lactate cotransporter (MCT1).
@en
prefLabel
Studies of the membrane topology of the rat erythrocyte H+/lactate cotransporter (MCT1).
@en
P2860
P356
P1433
P1476
Studies of the membrane topology of the rat erythrocyte H+/lactate cotransporter (MCT1).
@en
P2093
P2860
P304
P356
10.1042/BJ3200817
P407
P478
320 ( Pt 3)
P577
1996-12-01T00:00:00Z