Mutagenesis of the active site of the human Theta-class glutathione transferase GSTT2-2: catalysis with different substrates involves different residues.
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Zeta, a novel class of glutathione transferases in a range of species from plants to humansEvidence that human class Theta glutathione S-transferase T1-1 can catalyse the activation of dichloromethane, a liver and lung carcinogen in the mouse. Comparison of the tissue distribution of GST T1-1 with that of classes Alpha, Mu and Pi GST in hGenetic variations in human glutathione transferase enzymes: significance for pharmacology and toxicologyIdentification, characterization, and crystal structure of the Omega class glutathione transferasesGene structure, expression and chromosomal localization of murine theta class glutathione transferase mGSTT1-1Identification and characterization of GSTT3, a third murine Theta class glutathione transferaseGlutathione-binding site of a bombyx mori theta-class glutathione transferaseHuman glutathione transferase T2-2 discloses some evolutionary strategies for optimization of the catalytic activity of glutathione transferases.Molecular cloning, expression and site-directed mutagenesis of glutathione S-transferase from Ochrobactrum anthropiDifferential roles of tau class glutathione S-transferases in oxidative stress.Glutathione transferases: a structural perspective.Prediction of substrates for glutathione transferases by covalent docking.Glutathione s-transferases in pediatric cancer.Mutagenic analysis of conserved arginine residues in and around the novel sulfate binding pocket of the human Theta class glutathione transferase T2-2.The impact of nitric oxide toxicity on the evolution of the glutathione transferase superfamily: a proposal for an evolutionary driving forceGlutathione Transferase (GST)-Activated Prodrugs.Mechanisms of induction of cytosolic and microsomal glutathione transferase (GST) genes by xenobiotics and pro-inflammatory agents.A sensitive core region in the structure of glutathione S-transferases.GSTT2, a phase II gene induced by apple polyphenols, protects colon epithelial cells against genotoxic damage.Catalytic function of an ε-class glutathione S-transferase of the silkworm.Characterization of an omega-class glutathione S-transferase in the stress response of the silkmoth.Glutamate-64, a newly identified residue of the functionally conserved electron-sharing network contributes to catalysis and structural integrity of glutathione transferasesA functionally conserved basic residue in glutathione transferases interacts with the glycine moiety of glutathione and is pivotal for enzyme catalysis.Proton release on binding of glutathione to alpha, Mu and Delta class glutathione transferases.Clarification of the role of key active site residues of glutathione transferase zeta/maleylacetoacetate isomerase by a new spectrophotometric technique.Human glutathione transferase T2-2 discloses some evolutionary strategies for optimization of substrate binding to the active site of glutathione transferases.An electron-sharing network involved in the catalytic mechanism is functionally conserved in different glutathione transferase classes.Catalytic mechanism and role of hydroxyl residues in the active site of theta class glutathione S-transferases. Investigation of Ser-9 and Tyr-113 in a glutathione S-transferase from the Australian sheep blowfly, Lucilia cuprina.A homology model for the human theta-class glutathione transferase T1-1.
P2860
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P2860
Mutagenesis of the active site of the human Theta-class glutathione transferase GSTT2-2: catalysis with different substrates involves different residues.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Mutagenesis of the active site ...... s involves different residues.
@en
type
label
Mutagenesis of the active site ...... s involves different residues.
@en
prefLabel
Mutagenesis of the active site ...... s involves different residues.
@en
P2093
P2860
P356
P1433
P1476
Mutagenesis of the active site ...... s involves different residues.
@en
P2093
P2860
P304
P356
10.1042/BJ3190315
P407
P478
319 ( Pt 1)
P577
1996-10-01T00:00:00Z