Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and Activated
about
Dynamics of the IFT machinery at the ciliary tip.Diverse mitotic functions of the cytoskeletal cross-linking protein Shortstop suggest a role in Dynein/Dynactin activity.She1 affects dynein through direct interactions with the microtubule and the dynein microtubule-binding domain.A small-molecule activator of kinesin-1 drives remodeling of the microtubule network.A brief introduction of cryo-EM revolution-the Nobel Prize in Chemistry 2017.Cryo-EM shows how dynactin recruits two dyneins for faster movement.Cryo-electron tomography reveals that dynactin recruits a team of dyneins for processive motility.A conserved interaction of the dynein light intermediate chain with dynein-dynactin effectors necessary for processivity.Switching dynein motors on and off.Kinesins relocalize the chromosomal passenger complex to the midzone for spindle disassembly.Structural atlas of dynein motors at atomic resolution.Electron cryomicroscopy as a powerful tool in biomedical research.Recruitment of two dyneins to an mRNA-dependent Bicaudal D transport complexRNA-directed activation of cytoplasmic dynein-1 in reconstituted transport RNPsDynein-Dynactin-NuMA clusters generate cortical spindle-pulling forces as a multi-arm ensembleStep Sizes and Rate Constants of Single-headed Cytoplasmic Dynein Measured with Optical TweezersOptogenetic dissection of mitotic spindle positioning in vivoA mathematical understanding of how cytoplasmic dynein walks on microtubules
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P2860
Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and Activated
description
2017 nî lūn-bûn
@nan
2017年の論文
@ja
2017年論文
@yue
2017年論文
@zh-hant
2017年論文
@zh-hk
2017年論文
@zh-mo
2017年論文
@zh-tw
2017年论文
@wuu
2017年论文
@zh
2017年论文
@zh-cn
name
Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and Activated
@en
type
label
Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and Activated
@en
prefLabel
Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and Activated
@en
P2860
P50
P1433
P1476
Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and Activated
@en
P2093
Arnaud Rondelet
Helen E Foster
P2860
P304
1303-1314.e18
P356
10.1016/J.CELL.2017.05.025
P407
P577
2017-06-06T00:00:00Z