Triptolide Promotes Senescence of Prostate Cancer Cells Through Histone Methylation and Heterochromatin Formation

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Triptolide Promotes Senescence of Prostate Cancer Cells Through Histone Methylation and Heterochromatin Formation

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2017 nî lūn-bûn

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2017年の論文

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2017年論文

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2017年論文

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2017年論文

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2017年論文

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2017年論文

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Triptolide Promotes Senescence ...... and Heterochromatin Formation

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Triptolide Promotes Senescence ...... and Heterochromatin Formation

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Triptolide Promotes Senescence ...... and Heterochromatin Formation

@en

P1476

Triptolide Promotes Senescence ...... and Heterochromatin Formation

@en

P2093

Ming Lei

http://www.w3.org/2001/XMLSchema#string

P2860

Translating the Histone Code

A Suv39h-dependent mechanism for silencing S-phase genes in differentiating but not in cycling cells.

Structure-function analysis of SUV39H1 reveals a dominant role in heterochromatin organization, chromosome segregation, and mitotic progression.

Targeting EZH2 in cancer

Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins

Chromatin modifications and their function

Triptolide inhibits the proliferation of prostate cancer cells and down-regulates SUMO-specific protease 1 expression

Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence

Triptolide (TPL) inhibits global transcription by inducing proteasome-dependent degradation of RNA polymerase II (Pol II).

The epigenetics of cancer etiology.

P304

2519-2526

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P31

scholarly article

P356

10.22034/APJCP.2017.18.9.2519

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http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

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O Tamgue

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2017-09-27T00:00:00Z

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P698

28952292

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P932

5720660

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Triptolide Promotes Senescence of Prostate Cancer Cells Through Histone Methylation and Heterochromatin Formation

about

Triptolide Promotes Senescence of Prostate Cancer Cells Through Histone Methylation and Heterochromatin Formation

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P932