Drug efflux by a small multidrug resistance protein is inhibited by a transmembrane peptide.
about
A structured loop modulates coupling between the substrate-binding and dimerization domains in the multidrug resistance transporter EmrE.EmrE dimerization depends on membrane environment.Rationally designed transmembrane peptide mimics of the multidrug transporter protein Cdr1 act as antagonists to selectively block drug efflux and chemosensitize azole-resistant clinical isolates of Candida albicans.Efflux by small multidrug resistance proteins is inhibited by membrane-interactive helix-stapled peptides.
P2860
Drug efflux by a small multidrug resistance protein is inhibited by a transmembrane peptide.
description
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name
Drug efflux by a small multidr ...... ed by a transmembrane peptide.
@en
type
label
Drug efflux by a small multidr ...... ed by a transmembrane peptide.
@en
prefLabel
Drug efflux by a small multidr ...... ed by a transmembrane peptide.
@en
P2860
P356
P1476
Drug efflux by a small multidr ...... ed by a transmembrane peptide.
@en
P2093
Bradley E Poulsen
Charles M Deber
P2860
P304
P356
10.1128/AAC.00158-12
P407
P577
2012-04-23T00:00:00Z