Proteolytic cleavage of ataxin-7 promotes SCA7 retinal degeneration and neurological dysfunction.

about

Interactome network analysis identifies multiple caspase-6 interactors involved in the pathogenesis of HD.Roles of Post-translational Modifications in Spinocerebellar Ataxias

P2860

Q38791517-4C2CB624-1A40-4280-AD4A-08103148B5BF Q57072576-043EAA75-1A9C-4336-B007-D69A57D0BA5F

P2860

Proteolytic cleavage of ataxin-7 promotes SCA7 retinal degeneration and neurological dysfunction.

Item

http://www.wikidata.org/entity/Q41998176

description

2015 nî lūn-bûn

@nan

2015年の論文

@ja

2015年論文

@yue

2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

2015年论文

@wuu

2015年论文

@zh

2015年论文

@zh-cn

name

Proteolytic cleavage of ataxin ...... and neurological dysfunction.

@en

type

Item

label

Proteolytic cleavage of ataxin ...... and neurological dysfunction.

@en

prefLabel

Proteolytic cleavage of ataxin ...... and neurological dysfunction.

@en

P1476

Proteolytic cleavage of ataxin ...... and neurological dysfunction.

@en

P2093

Albert R La Spada

http://www.w3.org/2001/XMLSchema#string

Amy Lin

http://www.w3.org/2001/XMLSchema#string

Bryce L Sopher

http://www.w3.org/2001/XMLSchema#string

Lisa M Ellerby

http://www.w3.org/2001/XMLSchema#string

Sara K Custer

http://www.w3.org/2001/XMLSchema#string

Shona S Mookerjee

http://www.w3.org/2001/XMLSchema#string

Stephan J Guyenet

http://www.w3.org/2001/XMLSchema#string

Sylvia F Chen

http://www.w3.org/2001/XMLSchema#string

P2860

Cleavage of atrophin-1 at caspase site aspartic acid 109 modulates cytotoxicity

Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo

ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats

A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing

Cloning of the SCA7 gene reveals a highly unstable CAG repeat expansion

Expression analysis of the ataxin-1 protein in tissues from normal and spinocerebellar ataxia type 1 individuals

Ataxin-7 is a subunit of GCN5 histone acetyltransferase-containing complexes

Yeast Ataxin-7 links histone deubiquitination with gene gating and mRNA export.

Polyglutamine-expanded ataxin-7 antagonizes CRX function and induces cone-rod dystrophy in a mouse model of SCA7

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

P304

3908-3917

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1093/HMG/DDV121

http://www.w3.org/2001/XMLSchema#string

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P577

2015-04-09T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

25859008

http://www.w3.org/2001/XMLSchema#string

P932

4476441

http://www.w3.org/2001/XMLSchema#string

Proteolytic cleavage of ataxin-7 promotes SCA7 retinal degeneration and neurological dysfunction.

about

P2860

P2860

Proteolytic cleavage of ataxin-7 promotes SCA7 retinal degeneration and neurological dysfunction.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698

P932