Mutation in the U2 snRNA influences exon interactions of U5 snRNA loop 1 during pre-mRNA splicing.
about
The RNA binding protein Cwc2 interacts directly with the U6 snRNA to link the nineteen complex to the spliceosome during pre-mRNA splicingFunctional interactions between Prp8, Prp18, Slu7, and U5 snRNA during the second step of pre-mRNA splicing.Spliceosomal snRNA modifications and their function.Mutation of a U2 snRNA gene causes global disruption of alternative splicing and neurodegenerationSplint ligation of RNA with T4 DNA ligaseThe Prp18 protein stabilizes the interaction of both exons with the U5 snRNA during the second step of pre-mRNA splicingThe U1, U2 and U5 snRNAs crosslink to the 5' exon during yeast pre-mRNA splicing.The mechanism of the second step of pre-mRNA splicing.Insights into branch nucleophile positioning and activation from an orthogonal pre-mRNA splicing system in yeast.The U5 snRNA internal loop 1 is a platform for Brr2, Snu114 and Prp8 protein binding during U5 snRNP assembly.Evidence that U2/U6 helix I promotes both catalytic steps of pre-mRNA splicing and rearranges in between these steps.The NineTeen Complex (NTC) and NTC-associated proteins as targets for spliceosomal ATPase action during pre-mRNA splicing.In vitro reconstitution of yeast splicing with U4 snRNA reveals multiple roles for the 3' stem-loopAnalysis of synthetic lethality reveals genetic interactions between the GTPase Snu114p and snRNAs in the catalytic core of the Saccharomyces cerevisiae spliceosome.Mutations in the U5 snRNA result in altered splicing of subsets of pre-mRNAs and reduced stability of Prp8.Powering a two-stroke RNA engine.
P2860
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P2860
Mutation in the U2 snRNA influences exon interactions of U5 snRNA loop 1 during pre-mRNA splicing.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
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2006年论文
@zh-cn
name
Mutation in the U2 snRNA influ ...... op 1 during pre-mRNA splicing.
@en
type
label
Mutation in the U2 snRNA influ ...... op 1 during pre-mRNA splicing.
@en
prefLabel
Mutation in the U2 snRNA influ ...... op 1 during pre-mRNA splicing.
@en
P2093
P2860
P356
P1433
P1476
Mutation in the U2 snRNA influ ...... op 1 during pre-mRNA splicing.
@en
P2093
Elaine M Tatum
Joanne C McGrail
Raymond T O'Keefe
P2860
P304
P356
10.1038/SJ.EMBOJ.7601258
P407
P577
2006-08-03T00:00:00Z