Tricking an ancient immune function to eradicate hepatocellular carcinoma.

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Dietary fructose-induced hepatocellular carcinoma development manifested in mice lacking apoptosis inhibitor of macrophage (AIM).Independent modes of disease repair by AIM protein distinguished in AIM-felinized mice

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Tricking an ancient immune function to eradicate hepatocellular carcinoma.

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http://www.wikidata.org/entity/Q41999933

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2015 nî lūn-bûn

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2015年の論文

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2015年論文

@yue

2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

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2015年論文

@zh-tw

2015年论文

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2015年论文

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name

Tricking an ancient immune function to eradicate hepatocellular carcinoma.

@en

type

Item

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Tricking an ancient immune function to eradicate hepatocellular carcinoma.

@en

prefLabel

Tricking an ancient immune function to eradicate hepatocellular carcinoma.

@en

P1476

Tricking an ancient immune function to eradicate hepatocellular carcinoma.

@en

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Satoko Arai

http://www.w3.org/2001/XMLSchema#string

Toru Miyazaki

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Nonalcoholic fatty liver disease

Membrane complement regulatory proteins: insight from animal studies and relevance to human diseases.

Circulating AIM as an indicator of liver damage and hepatocellular carcinoma in humans.

LXR-dependent gene expression is important for macrophage survival and the innate immune response.

A role for the apoptosis inhibitory factor AIM/Spalpha/Api6 in atherosclerosis development.

Macrophage-derived AIM is endocytosed into adipocytes and decreases lipid droplets via inhibition of fatty acid synthase activity.

Increased susceptibility of thymocytes to apoptosis in mice lacking AIM, a novel murine macrophage-derived soluble factor belonging to the scavenger receptor cysteine-rich domain superfamily.

Obesity-associated autoantibody production requires AIM to retain the immunoglobulin M immune complex on follicular dendritic cells.

Apoptosis inhibitor of macrophage (AIM) diminishes lipid droplet-coating proteins leading to lipolysis in adipocytes.

Circulating AIM Prevents Hepatocellular Carcinoma through Complement Activation

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e985915

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scholarly article

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10.4161/23723556.2014.985915

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http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

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2015-01-23T00:00:00Z

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273278746

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27308467

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P932

4905303

http://www.w3.org/2001/XMLSchema#string

Tricking an ancient immune function to eradicate hepatocellular carcinoma.

about

P2860

P2860

Tricking an ancient immune function to eradicate hepatocellular carcinoma.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P5875

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P5875

P698

P932