SIRT3 is regulated by nutrient excess and modulates hepatic susceptibility to lipotoxicity - Wikidata - wikimedia - TriplyDB

SIRT3 is regulated by nutrient excess and modulates hepatic susceptibility to lipotoxicity

SIRT3 is regulated by nutrient excess and modulates hepatic susceptibility to lipotoxicity

http://www.wikidata.org/entity/Q42006558

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Identification of a molecular component of the mitochondrial acetyltransferase programme: a novel role for GCN5L1 SIRT3 deacetylates and activates OPA1 to regulate mitochondrial dynamics during stress Sirtuin 1 and sirtuin 3: physiological modulators of metabolism SIRT3 regulates progression and development of diseases of aging.Regulation of Akt signaling by sirtuins: its implication in cardiac hypertrophy and aging SIRT3 as a Regulator of Non-alcoholic Fatty Liver Disease Sirtuins, metabolism, and DNA repair Role of mitochondria in nonalcoholic fatty liver disease Redox control of senescence and age-related disease SIRT3 in Cardiac Physiology and Disease Sirtuins and nonalcoholic fatty liver disease Metformin reduces hepatic expression of SIRT3, the mitochondrial deacetylase controlling energy metabolism SIRT3-dependent deacetylation exacerbates acetaminophen hepatotoxicity Berberine promotes glucose consumption independently of AMP-activated protein kinase activation Targeting sirtuins for the treatment of diabetes Maternal obesity during gestation impairs fatty acid oxidation and mitochondrial SIRT3 expression in rat offspring at weaning SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome.Hepatic FoxOs regulate lipid metabolism via modulation of expression of the nicotinamide phosphoribosyltransferase gene.Prolonged fasting identifies heat shock protein 10 as a Sirtuin 3 substrate: elucidating a new mechanism linking mitochondrial protein acetylation to fatty acid oxidation enzyme folding and function.Caloric excess or restriction mediated modulation of metabolic enzyme acetylation-proposed effects on cardiac growth and function.Mitochondrial sirtuins and their relationships with metabolic disease and cancer.Emerging characterization of the role of SIRT3-mediated mitochondrial protein deacetylation in the heart Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3 The role of sirtuins in modulating redox stressors Using mitochondrial sirtuins as drug targets: disease implications and available compounds.Fatty liver is associated with reduced SIRT3 activity and mitochondrial protein hyperacetylation SIRT3-SOD2-mROS-dependent autophagy in cadmium-induced hepatotoxicity and salvage by melatonin.Fasting and refeeding differentially regulate NLRP3 inflammasome activation in human subjects.Mitochondrial metabolism, sirtuins, and aging Mitochondrial protein acylation and intermediary metabolism: regulation by sirtuins and implications for metabolic disease.PGC-1α/ERRα-Sirt3 Pathway Regulates DAergic Neuronal Death by Directly Deacetylating SOD2 and ATP Synthase β.The sirtuin family's role in aging and age-associated pathologies.Mechanisms and Dynamics of Protein Acetylation in Mitochondria.Sirtuin 3 (SIRT3) Regulates α-Smooth Muscle Actin (α-SMA) Production through the Succinate Dehydrogenase-G Protein-coupled Receptor 91 (GPR91) Pathway in Hepatic Stellate Cells.Altered cellular redox status, sirtuin abundance and clock gene expression in a mouse model of developmentally primed NASH.Sirtuin 3: A major control point for obesity-related metabolic diseases?Developmental programming of pediatric nonalcoholic fatty liver disease: redefining the"first hit".Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation Obesity and Cardiac Function - The Role of Caloric Excess and its Reversal.SIRT3 overexpression antagonizes high glucose accelerated cellular senescence in human diploid fibroblasts via the SIRT3-FOXO1 signaling pathway.

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P2860

SIRT3 is regulated by nutrient excess and modulates hepatic susceptibility to lipotoxicity

http://www.wikidata.org/entity/Q42006558

description

2010 nî lūn-bûn

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2010年の論文

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年学术文章

@zh-sg

2010年學術文章

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2010年學術文章

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2010年學術文章

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name

SIRT3 is regulated by nutrient ...... susceptibility to lipotoxicity

@en

SIRT3 is regulated by nutrient ...... susceptibility to lipotoxicity

@nl

type

label

SIRT3 is regulated by nutrient ...... susceptibility to lipotoxicity

@en

SIRT3 is regulated by nutrient ...... susceptibility to lipotoxicity

@nl

prefLabel

SIRT3 is regulated by nutrient ...... susceptibility to lipotoxicity

@en

SIRT3 is regulated by nutrient ...... susceptibility to lipotoxicity

@nl

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J.FREERADBIOMED.2010.07.009

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Free Radical Biology and Medicine

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SIRT3 is regulated by nutrient ...... susceptibility to lipotoxicity

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Christopher C Dimond

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David Gius

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Iain Scott

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Jianjun Bao

http://www.w3.org/2001/XMLSchema#string

Liyan Pang

http://www.w3.org/2001/XMLSchema#string

Michael N Sack

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Zhongping Lu

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P2860

Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2

Regulation of cellular metabolism by protein lysine acetylation

Identification and characterization of proteins interacting with SIRT1 and SIRT3: implications in the anti-aging and metabolic effects of sirtuins

Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5

SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress

SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70

Substrate and functional diversity of lysine acetylation revealed by a proteomics survey

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation

A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis

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