SIRT3 is regulated by nutrient excess and modulates hepatic susceptibility to lipotoxicity
about
Identification of a molecular component of the mitochondrial acetyltransferase programme: a novel role for GCN5L1SIRT3 deacetylates and activates OPA1 to regulate mitochondrial dynamics during stressSirtuin 1 and sirtuin 3: physiological modulators of metabolismSIRT3 regulates progression and development of diseases of aging.Regulation of Akt signaling by sirtuins: its implication in cardiac hypertrophy and agingSIRT3 as a Regulator of Non-alcoholic Fatty Liver DiseaseSirtuins, metabolism, and DNA repairRole of mitochondria in nonalcoholic fatty liver diseaseRedox control of senescence and age-related diseaseSIRT3 in Cardiac Physiology and DiseaseSirtuins and nonalcoholic fatty liver diseaseMetformin reduces hepatic expression of SIRT3, the mitochondrial deacetylase controlling energy metabolismSIRT3-dependent deacetylation exacerbates acetaminophen hepatotoxicityBerberine promotes glucose consumption independently of AMP-activated protein kinase activationTargeting sirtuins for the treatment of diabetesMaternal obesity during gestation impairs fatty acid oxidation and mitochondrial SIRT3 expression in rat offspring at weaningSIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome.Hepatic FoxOs regulate lipid metabolism via modulation of expression of the nicotinamide phosphoribosyltransferase gene.Prolonged fasting identifies heat shock protein 10 as a Sirtuin 3 substrate: elucidating a new mechanism linking mitochondrial protein acetylation to fatty acid oxidation enzyme folding and function.Caloric excess or restriction mediated modulation of metabolic enzyme acetylation-proposed effects on cardiac growth and function.Mitochondrial sirtuins and their relationships with metabolic disease and cancer.Emerging characterization of the role of SIRT3-mediated mitochondrial protein deacetylation in the heartHonokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3The role of sirtuins in modulating redox stressorsUsing mitochondrial sirtuins as drug targets: disease implications and available compounds.Fatty liver is associated with reduced SIRT3 activity and mitochondrial protein hyperacetylationSIRT3-SOD2-mROS-dependent autophagy in cadmium-induced hepatotoxicity and salvage by melatonin.Fasting and refeeding differentially regulate NLRP3 inflammasome activation in human subjects.Mitochondrial metabolism, sirtuins, and agingMitochondrial protein acylation and intermediary metabolism: regulation by sirtuins and implications for metabolic disease.PGC-1α/ERRα-Sirt3 Pathway Regulates DAergic Neuronal Death by Directly Deacetylating SOD2 and ATP Synthase β.The sirtuin family's role in aging and age-associated pathologies.Mechanisms and Dynamics of Protein Acetylation in Mitochondria.Sirtuin 3 (SIRT3) Regulates α-Smooth Muscle Actin (α-SMA) Production through the Succinate Dehydrogenase-G Protein-coupled Receptor 91 (GPR91) Pathway in Hepatic Stellate Cells.Altered cellular redox status, sirtuin abundance and clock gene expression in a mouse model of developmentally primed NASH.Sirtuin 3: A major control point for obesity-related metabolic diseases?Developmental programming of pediatric nonalcoholic fatty liver disease: redefining the"first hit".Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulationObesity and Cardiac Function - The Role of Caloric Excess and its Reversal.SIRT3 overexpression antagonizes high glucose accelerated cellular senescence in human diploid fibroblasts via the SIRT3-FOXO1 signaling pathway.
P2860
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P2860
SIRT3 is regulated by nutrient excess and modulates hepatic susceptibility to lipotoxicity
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
SIRT3 is regulated by nutrient ...... susceptibility to lipotoxicity
@en
SIRT3 is regulated by nutrient ...... susceptibility to lipotoxicity
@nl
type
label
SIRT3 is regulated by nutrient ...... susceptibility to lipotoxicity
@en
SIRT3 is regulated by nutrient ...... susceptibility to lipotoxicity
@nl
prefLabel
SIRT3 is regulated by nutrient ...... susceptibility to lipotoxicity
@en
SIRT3 is regulated by nutrient ...... susceptibility to lipotoxicity
@nl
P2093
P2860
P1476
SIRT3 is regulated by nutrient ...... susceptibility to lipotoxicity
@en
P2093
Christopher C Dimond
David Gius
Iain Scott
Jianjun Bao
Liyan Pang
Michael N Sack
Zhongping Lu
P2860
P304
P356
10.1016/J.FREERADBIOMED.2010.07.009
P577
2010-07-18T00:00:00Z