Hypertension induces brain β-amyloid accumulation, cognitive impairment, and memory deterioration through activation of receptor for advanced glycation end products in brain vasculature.
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Hypertension and Dementia: Epidemiological and Experimental Evidence Revealing a Detrimental RelationshipHypertension: a harbinger of stroke and dementiaHypertension and cognitive dysfunction in elderly: blood pressure management for this global burdenDefining the Relationship Between Hypertension, Cognitive Decline, and Dementia: a Review.Critical role of matrix metalloprotease-9 in chronic high fat diet-induced cerebral vascular remodelling and increase of ischaemic brain injury in mice†.Mouse models to study the effect of cardiovascular risk factors on brain structure and cognitionInflammation-induced dysfunction of the low-density lipoprotein receptor-related protein-1 at the blood-brain barrier: protection by the antioxidant N-acetylcysteine.Receptor for advanced glycation endproduct modulators: a new therapeutic target in Alzheimer's disease.Vascular and parenchymal amyloid pathology in an Alzheimer disease knock-in mouse model: interplay with cerebral blood flow.Chronic Hypertension Leads to Neurodegeneration in the TgSwDI Mouse Model of Alzheimer's DiseaseThe Age-Dependent Relationship between Blood Pressure and Cognitive Impairment: A Cross-Sectional Study in a Rural Area of Xi'an, ChinaLearning on Jupiter, learning on the Moon: the dark side of the G-force. Effects of gravity changes on neurovascular unit and modulation of learning and memoryThe independent association of hypertension with cognitive function among older adults with heart failureThe Spleen: A Hub Connecting Nervous and Immune Systems in Cardiovascular and Metabolic DiseasesThe neuropathology and cerebrovascular mechanisms of dementiaHypertension enhances Aβ-induced neurovascular dysfunction, promotes β-secretase activity, and leads to amyloidogenic processing of APPHigh-mobility group box 1 from reactive astrocytes enhances the accumulation of endothelial progenitor cells in damaged white matter.Neurovascular dysfunction and neurodegeneration in dementia and Alzheimer's diseaseRecent Developments in Understanding Brain Aging: Implications for Alzheimer's Disease and Vascular Cognitive Impairment.p38 MAPK Inhibition Improves Synaptic Plasticity and Memory in Angiotensin II-dependent Hypertensive MiceA high-salt diet further impairs age-associated declines in cognitive, behavioral, and cardiovascular functions in male Fischer brown Norway rats.Potential of the angiotensin receptor blockers (ARBs) telmisartan, irbesartan, and candesartan for inhibiting the HMGB1/RAGE axis in prevention and acute treatment of stroke.Synergistic effects of hypertension and aging on cognitive function and hippocampal expression of genes involved in β-amyloid generation and Alzheimer's disease.Role of 20-HETE, TRPC channels, and BKCa in dysregulation of pressure-induced Ca2+ signaling and myogenic constriction of cerebral arteries in aged hypertensive mice.Neurovascular signaling in the brain and the pathological consequences of hypertension.Pathophysiological Links Among Hypertension and Alzheimer's Disease.Enhanced interstitial fluid drainage in the hippocampus of spontaneously hypertensive rats.Expression and Processing of Amyloid Precursor Protein in Vascular Endothelium.High-Sodium Diet Has Opposing Effects on Mean Arterial Blood Pressure and Cerebral Perfusion in a Transgenic Mouse Model of Alzheimer's Disease.The receptor for advanced glycation end products is required for β-catenin stabilization in a chemical-induced asthma model.Effects of Hypertension and Anti-Hypertensive Treatment on Amyloid-β (Aβ) Plaque Load and Aβ-Synthesizing and Aβ-Degrading Enzymes in Frontal Cortex.Vascular Dysfunction in a Transgenic Model of Alzheimer's Disease: Effects of CB1R and CB2R Cannabinoid Agonists.Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for cerebromicrovascular and brain aging.Perivascular spaces, glymphatic dysfunction, and small vessel disease.Antihypertensive drug Valsartan promotes dendritic spine density by altering AMPA receptor trafficking.The heart-brain connection: mechanistic insights and modelsVascular risk factors: a ticking time bomb to Alzheimer's disease.Vascular risk factors and mild cognitive impairment in the elderly population in Southwest China.APP/Aβ structural diversity and Alzheimer's disease pathogenesis.Soluble receptor for advanced glycation end products mitigates vascular dysfunction in spontaneously hypertensive rats.
P2860
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P2860
Hypertension induces brain β-amyloid accumulation, cognitive impairment, and memory deterioration through activation of receptor for advanced glycation end products in brain vasculature.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Hypertension induces brain β-a ...... products in brain vasculature.
@en
Hypertension induces brain β-a ...... products in brain vasculature.
@nl
type
label
Hypertension induces brain β-a ...... products in brain vasculature.
@en
Hypertension induces brain β-a ...... products in brain vasculature.
@nl
prefLabel
Hypertension induces brain β-a ...... products in brain vasculature.
@en
Hypertension induces brain β-a ...... products in brain vasculature.
@nl
P2093
P2860
P1433
P1476
Hypertension induces brain β-a ...... products in brain vasculature.
@en
P2093
Berislav Zlokovic
Daniela Carnevale
Fabio Pallante
Giada Mascio
Giuseppe Lembo
Igor Branchi
Ivana D'Andrea
Robert D Bell
Shirley Shidu Yan
Valentina Fardella
P2860
P304
P356
10.1161/HYPERTENSIONAHA.112.195511
P407
P577
2012-05-21T00:00:00Z