Pre-association of polynuclear platinum anticancer agents on a protein, human serum albumin. Implications for drug design.

Pre-association of polynuclear platinum anticancer agents on a protein, human serum albumin. Implications for drug design.

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http://www.wikidata.org/entity/Q42012350
Factors affecting DNA-DNA interstrand cross-links in the antiparallel 3'-3' sense: a comparison with the 5'-5' directional isomer.Combining aspects of the platinum anticancer drugs picoplatin and BBR3464 to synthesize a new family of sterically hindered dinuclear complexes; their synthesis, binding kinetics and cytotoxicity.Excursions in polynuclear platinum DNA binding.The trans influence in the modulation of platinum anticancer agent biology: the effect of nitrite leaving group on aquation, reactions with S-nucleophiles and DNA binding of dinuclear and trinuclear compounds.Understanding the interaction of an antitumoral platinum(II) 7-azaindolate complex with proteins and DNA.Effects of noncovalent platinum drug-protein interactions on drug efficacy: use of fluorescent conjugates as probes for drug metabolism.Solution studies of dinuclear polyamine-linked platinum-based antitumour complexes.Investigations of the binding of [Pt2(DTBPA)Cl2](II) and [Pt2(TPXA)Cl2](II) to DNA via various cross-linking modes.Application of mass spectrometric techniques to delineate the modes-of-action of anticancer metallodrugs.Multi-platinum anti-cancer agents. Substitution-inert compounds for tumor selectivity and new targets.Studying the interactions of a platinum(II) 9-aminoacridine complex with proteins and oligonucleotides by ESI-TOF MS.Amide-based prodrugs of spermidine-bridged dinuclear platinum. Synthesis, DNA binding, and biological activity.Platinum and Palladium Polyamine Complexes as Anticancer Agents: The Structural Factor
P2860

Pre-association of polynuclear platinum anticancer agents on a protein, human serum albumin. Implications for drug design.

Item
http://www.wikidata.org/entity/Q42012350
description
2007 nî lūn-bûn
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2007年の論文
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2007年学术文章
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2007年学术文章
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2007年学术文章
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2007年学术文章
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2007年学术文章
@zh-sg
2007年學術文章
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2007年學術文章
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2007年學術文章
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name
Pre-association of polynuclear ...... Implications for drug design.
@en
Pre-association of polynuclear ...... Implications for drug design.
@nl
type
label
Pre-association of polynuclear ...... Implications for drug design.
@en
Pre-association of polynuclear ...... Implications for drug design.
@nl
prefLabel
Pre-association of polynuclear ...... Implications for drug design.
@en
Pre-association of polynuclear ...... Implications for drug design.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P577
P5875
P698
P921
P932
P356
P1433
P1476
Pre-association of polynuclear ...... Implications for drug design.
@en
P2093
P2860
P304
P31
P356
P407
P433
P577
P5875
P698
P921
P932