Inhibition of autophagy, lysosome and VCP function impairs stress granule assembly.
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Alterations in stress granule dynamics driven by TDP-43 and FUS: a link to pathological inclusions in ALS?Autophagy and Neurodegeneration: Insights from a Cultured Cell Model of ALSAre aberrant phase transitions a driver of cellular aging?The Myoblast C2C12 Transfected with Mutant Valosin-Containing Protein Exhibits Delayed Stress Granule Resolution on Oxidative Stress.RNA-sequencing Identifies Novel Pathways in Sarcoidosis Monocytes.An aberrant phase transition of stress granules triggered by misfolded protein and prevented by chaperone function.The Role of the Heat Shock Protein B8 (HSPB8) in Motoneuron Diseases.NEDD4 controls spermatogonial stem cell homeostasis and stress response by regulating messenger ribonucleoprotein complexes.Granulostasis: Protein Quality Control of RNP Granules.Altered mRNP granule dynamics in FTLD pathogenesis.Phosphatidic Acid Increases Epidermal Growth Factor Receptor Expression by Stabilizing mRNA Decay and by Inhibiting Lysosomal and Proteasomal Degradation of the Internalized Receptorp73 regulates basal and starvation-induced liver metabolism in vivo.Valosin-containing protein is a key mediator between autophagic cell death and apoptosis in adult hippocampal neural stem cells following insulin withdrawal.Pathogenic Mutations in the Valosin-containing Protein/p97(VCP) N-domain Inhibit the SUMOylation of VCP and Lead to Impaired Stress Response.C9ORF72 Regulates Stress Granule Formation and Its Deficiency Impairs Stress Granule Assembly, Hypersensitizing Cells to Stress.Stress granules at the intersection of autophagy and ALS.Molecular mechanisms of mTOR regulation by stressEmerging connections between RNA and autophagy.Subtilase cytotoxin produced by locus of enterocyte effacement-negative Shiga-toxigenic Escherichia coli induces stress granule formation.Autophagy Dysregulation in ALS: When Protein Aggregates Get Out of Hand.VCP inhibitors induce endoplasmic reticulum stress, cause cell cycle arrest, trigger caspase-mediated cell death and synergistically kill ovarian cancer cells in combination with Salubrinal.PLAA Mutations Cause a Lethal Infantile Epileptic Encephalopathy by Disrupting Ubiquitin-Mediated Endolysosomal Degradation of Synaptic Proteins.FYCO1 and autophagy control the integrity of the haploid male germ cell-specific RNP granules.Targeted transplantation of mitochondria to hepatocytes.Impaired spliceosomal UsnRNP assembly leads to Sm mRNA down-regulation and Sm protein degradation.Turnip mosaic virus counteracts selective autophagy of the viral silencing suppressor HCpro.TIA1 variant drives myodegeneration in multisystem proteinopathy with SQSTM1 mutations.Folliculin, a tumor suppressor associated with Birt-Hogg-Dubé (BHD) syndrome, is a novel modifier of TDP-43 cytoplasmic translocation and aggregation.Crosstalk Between Mammalian Autophagy and the Ubiquitin-Proteasome SystemIdentification of Novel Subcellular Localization and Trafficking of HIV-1 Nef Variants from Reference Strains G (F1.93.HH8793) and H (BE.93.VI997)
P2860
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P2860
Inhibition of autophagy, lysosome and VCP function impairs stress granule assembly.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Inhibition of autophagy, lysosome and VCP function impairs stress granule assembly.
@en
Inhibition of autophagy, lysosome and VCP function impairs stress granule assembly.
@nl
type
label
Inhibition of autophagy, lysosome and VCP function impairs stress granule assembly.
@en
Inhibition of autophagy, lysosome and VCP function impairs stress granule assembly.
@nl
prefLabel
Inhibition of autophagy, lysosome and VCP function impairs stress granule assembly.
@en
Inhibition of autophagy, lysosome and VCP function impairs stress granule assembly.
@nl
P2093
P2860
P50
P356
P1476
Inhibition of autophagy, lysosome and VCP function impairs stress granule assembly.
@en
P2093
D C Rubinsztein
F F Morelli
S J Seguin
P2860
P2888
P304
P356
10.1038/CDD.2014.103
P577
2014-07-18T00:00:00Z
P5875
P6179
1026535613