Design, synthesis, and structure-activity relationship exploration of 1-substituted 4-aroyl-3-hydroxy-5-phenyl-1H-pyrrol-2(5H)-one analogues as inhibitors of the annexin A2-S100A10 protein interaction.

Design, synthesis, and structure-activity relationship exploration of 1-substituted 4-aroyl-3-hydroxy-5-phenyl-1H-pyrrol-2(5H)-one analogues as inhibitors of the annexin A2-S100A10 protein interaction.

Item
http://www.wikidata.org/entity/Q42032160
Small molecule inhibitors of the annexin A2 heterotetramer prevent human papillomavirus type 16 infection.State-of-the-art strategies for targeting protein-protein interactions by small-molecule inhibitors.Disruption of Annexin II /p11 Interaction Suppresses Leukemia Cell Binding, Homing and Engraftment, and Sensitizes the Leukemia Cells to Chemotherapy.Functions of S100 proteins.In vivo screening of S100B inhibitors for melanoma therapy.Annexin A2 complexes with S100 proteins: structure, function and pharmacological manipulation.Design, synthesis and SAR exploration of tri-substituted 1,2,4-triazoles as inhibitors of the annexin A2-S100A10 protein interaction.Protein interactions between surface annexin A2 and S100A10 mediate adhesion of breast cancer cells to microvascular endothelial cells.Three-dimensional pharmacophore design and biochemical screening identifies substituted 1,2,4-triazoles as inhibitors of the annexin A2-S100A10 protein interaction.Src kinase-induced phosphorylation of annexin A2 mediates glucocorticoid resistance in MLL-rearranged infant acute lymphoblastic leukemia.4-Aroyl-3-hydroxy-5-phenyl-1H-pyrrol-2(5H)-ones as N-formyl peptide receptor 1 (FPR1) antagonists.Stereoselective Synthesis of Quaternary Pyrrolidine-2,3-diones and β-Amino Acids.Regulation of von-Willebrand Factor Secretion from Endothelial Cells by the Annexin A2-S100A10 Complex.
P2860

Design, synthesis, and structure-activity relationship exploration of 1-substituted 4-aroyl-3-hydroxy-5-phenyl-1H-pyrrol-2(5H)-one analogues as inhibitors of the annexin A2-S100A10 protein interaction.

Item
http://www.wikidata.org/entity/Q42032160
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Design, synthesis, and structu ...... 2-S100A10 protein interaction.
@en
Design, synthesis, and structu ...... 2-S100A10 protein interaction.
@nl
type
label
Design, synthesis, and structu ...... 2-S100A10 protein interaction.
@en
Design, synthesis, and structu ...... 2-S100A10 protein interaction.
@nl
prefLabel
Design, synthesis, and structu ...... 2-S100A10 protein interaction.
@en
Design, synthesis, and structu ...... 2-S100A10 protein interaction.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P921
P932
P356
P1433
P1476
Design, synthesis, and structu ...... A2-S100A10 protein interaction
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P921
P932