Cellular source of apolipoprotein E4 determines neuronal susceptibility to excitotoxic injury in transgenic mice
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Alzheimer mechanisms and therapeutic strategiesNeurodegeneration in a Drosophila model for the function of TMCC2, an amyloid protein precursor-interacting and apolipoprotein E-binding proteinThe dendritic hypothesis for Alzheimer's disease pathophysiology.Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapyNeighborhood psychosocial environment, apolipoprotein E genotype, and cognitive function in older adultsThe ε3 and ε4 alleles of human APOE differentially affect tau phosphorylation in hyperinsulinemic and pioglitazone treated miceStructure-dependent impairment of intracellular apolipoprotein E4 trafficking and its detrimental effects are rescued by small-molecule structure correctorsStem cell derived basal forebrain cholinergic neurons from Alzheimer's disease patients are more susceptible to cell death.Apolipoprotein E4 produced in GABAergic interneurons causes learning and memory deficits in miceApolipoprotein E: from lipid transport to neurobiologyCellular source-specific effects of apolipoprotein (apo) E4 on dendrite arborization and dendritic spine development.C-terminal-truncated apolipoprotein (apo) E4 inefficiently clears amyloid-beta (Abeta) and acts in concert with Abeta to elicit neuronal and behavioral deficits in mice.CNF1 increases brain energy level, counteracts neuroinflammatory markers and rescues cognitive deficits in a murine model of Alzheimer's disease.Introducing Human APOE into Aβ Transgenic Mouse Models.Multi-Target-Directed Ligands and other Therapeutic Strategies in the Search of a Real Solution for Alzheimer's Disease.Mouse models of Alzheimer's disease.Increased Aβ42-α7-like nicotinic acetylcholine receptor complex level in lymphocytes is associated with apolipoprotein E4-driven Alzheimer's disease pathogenesis.What are lipoproteins doing in the brain?Roles of apolipoprotein E4 (ApoE4) in the pathogenesis of Alzheimer's disease: lessons from ApoE mouse models.
P2860
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P2860
Cellular source of apolipoprotein E4 determines neuronal susceptibility to excitotoxic injury in transgenic mice
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
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2010年学术文章
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2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
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2010年學術文章
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name
Cellular source of apolipoprot ...... oxic injury in transgenic mice
@en
Cellular source of apolipoprot ...... oxic injury in transgenic mice
@nl
type
label
Cellular source of apolipoprot ...... oxic injury in transgenic mice
@en
Cellular source of apolipoprot ...... oxic injury in transgenic mice
@nl
prefLabel
Cellular source of apolipoprot ...... oxic injury in transgenic mice
@en
Cellular source of apolipoprot ...... oxic injury in transgenic mice
@nl
P2093
P2860
P1476
Cellular source of apolipoprot ...... oxic injury in transgenic mice
@en
P2093
Aubrey Bernardo
Gui-Qiu Yu
Jorge J Palop
Lennart Mucke
Manuel Buttini
Shengjun Chang
Tony Wyss-Coray
Yadong Huang
P2860
P304
P356
10.2353/AJPATH.2010.090973
P407
P577
2010-07-01T00:00:00Z