RGS6, RGS7, RGS9, and RGS11 stimulate GTPase activity of Gi family G-proteins with differential selectivity and maximal activity.
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RGS9-2: probing an intracellular modulator of behavior as a drug target.The R7 RGS protein family: multi-subunit regulators of neuronal G protein signalingSimultaneous stimulation of GABA and beta adrenergic receptors stabilizes isotypes of activated adenylyl cyclase heterocomplexEssential role of the m2R-RGS6-IKACh pathway in controlling intrinsic heart rate variabilityCrystal structure of the multifunctional Gβ5–RGS9 complexMolecular architecture of G o and the structural basis for RGS16-mediated deactivationRegulators of G-protein signaling in the heart and their potential as therapeutic targets.G protein betagamma11 complex translocation is induced by Gi, Gq and Gs coupling receptors and is regulated by the alpha subunit typeG beta 5.RGS7 inhibits G alpha q-mediated signaling via a direct protein-protein interactionR7BP augments the function of RGS7*Gbeta5 complexes by a plasma membrane-targeting mechanismR7BP complexes with RGS9-2 and RGS7 in the striatum differentially control motor learning and locomotor responses to cocaineD1 dopamine receptor signaling is modulated by the R7 RGS protein EAT-16 and the R7 binding protein RSBP-1 in Caenoerhabditis elegans motor neuronsPalmitoylation regulates plasma membrane-nuclear shuttling of R7BP, a novel membrane anchor for the RGS7 family.The RGS14 GoLoco domain discriminates among Galphai isoformsRSBP-1 is a membrane-targeting subunit required by the Galpha(q)-specific but not the Galpha(o)-specific R7 regulator of G protein signaling in Caenorhabditis elegans.RNA interference screen for RGS protein specificity at muscarinic and protease-activated receptors reveals bidirectional modulation of signaling.Structure of Galpha(i1) bound to a GDP-selective peptide provides insight into guanine nucleotide exchangeR7-binding protein targets the G protein beta 5/R7-regulator of G protein signaling complex to lipid rafts in neuronal cells and brain.Association of Rgs7/Gβ5 complexes with Girk channels and GABAB receptors in hippocampal CA1 pyramidal neurons.Functional redundancy of R7 RGS proteins in ON-bipolar cell dendritesGα16 interacts with tetratricopeptide repeat 1 (TPR1) through its β3 region to activate Ras independently of phospholipase Cβ signalingDifferential modulation of mu-opioid receptor signaling to adenylyl cyclase by regulators of G protein signaling proteins 4 or 8 and 7 in permeabilised C6 cells is Galpha subtype dependent.Differential effects of the Gβ5-RGS7 complex on muscarinic M3 receptor-induced Ca2+ influx and release.RGS17/RGSZ2, a novel regulator of Gi/o, Gz, and Gq signaling.Gi/o signaling and the palmitoyltransferase DHHC2 regulate palmitate cycling and shuttling of RGS7 family-binding protein.Reversible inhibitors of regulators of G-protein signaling identified in a high-throughput cell-based calcium signaling assay.An allosteric regulator of R7-RGS proteins influences light-evoked activity and glutamatergic waves in the inner retina.Regulator of G protein signaling 6 is a critical mediator of both reward-related behavioral and pathological responses to alcoholTargeted deletion of one or two copies of the G protein β subunit Gβ5 gene has distinct effects on body weight and behavior in mice.How regulators of G protein signaling achieve selective regulation.Gβ5-RGS complexes are gatekeepers of hyperactivity involved in control of multiple neurotransmitter systems.R7BP modulates opiate analgesia and tolerance but not withdrawal.Subcellular localization of regulator of G protein signaling RGS7 complex in neurons and transfected cells.R7BP: a surprising new link between G proteins, RGS proteins, and nuclear signaling in the brain.GIRK channel modulation by assembly with allosterically regulated RGS proteinsRoles for Regulator of G Protein Signaling Proteins in Synaptic Signaling and Plasticity.Postnatal induction and localization of R7BP, a membrane-anchoring protein for regulator of G protein signaling 7 family-Gbeta5 complexes in brain.The complex of G protein regulator RGS9-2 and Gβ(5) controls sensitization and signaling kinetics of type 5 adenylyl cyclase in the striatumIntermolecular Interaction between Anchoring Subunits Specify Subcellular Targeting and Function of RGS Proteins in Retina ON-Bipolar NeuronsGbeta5-RGS complexes co-localize with mGluR6 in retinal ON-bipolar cells
P2860
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P2860
RGS6, RGS7, RGS9, and RGS11 stimulate GTPase activity of Gi family G-proteins with differential selectivity and maximal activity.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
RGS6, RGS7, RGS9, and RGS11 st ...... ectivity and maximal activity.
@en
RGS6, RGS7, RGS9, and RGS11 st ...... ectivity and maximal activity.
@nl
type
label
RGS6, RGS7, RGS9, and RGS11 st ...... ectivity and maximal activity.
@en
RGS6, RGS7, RGS9, and RGS11 st ...... ectivity and maximal activity.
@nl
prefLabel
RGS6, RGS7, RGS9, and RGS11 st ...... ectivity and maximal activity.
@en
RGS6, RGS7, RGS9, and RGS11 st ...... ectivity and maximal activity.
@nl
P2093
P356
P1476
RGS6, RGS7, RGS9, and RGS11 st ...... ectivity and maximal activity.
@en
P2093
Andrejs M Krumins
Erik T Bodor
Gary L Waldo
James Corbitt
Shelley B Hooks
T Kendall Harden
P304
10087-10093
P356
10.1074/JBC.M211382200
P407
P577
2003-01-16T00:00:00Z