Proteolytic Cleavage of the Linker Region of the Human P-glycoprotein Modulates Its ATPase Function.
about
A gene optimization strategy that enhances production of fully functional P-glycoprotein in Pichia pastorisRapid loss of blood-brain barrier P-glycoprotein activity through transporter internalization demonstrated using a novel in situ proteolysis protection assay.MDR1 function is sensitive to the phosphorylation state of myosin regulatory light chainStructural characterization of two metastable ATP-bound states of P-glycoprotein.Expression of ATP-Binding Cassette Transporters B1 and C1 after Severe Traumatic Brain Injury in Humans.Aβ40 Reduces P-Glycoprotein at the Blood-Brain Barrier through the Ubiquitin-Proteasome Pathway.Assessing the Stabilization of P-Glycoprotein's Nucleotide-Binding Domains by the Linker, Using Molecular Dynamics.Allosteric modulation bypasses the requirement for ATP hydrolysis in regenerating low affinity transition state conformation of human P-glycoprotein.Identification of two different states of P-glycoprotein in its catalytic cycle: role of the linker region in the transition between these two states.Altered P-glycoprotein expression in AIDS patients with HIV encephalitis.
P2860
Q28476421-79D9246B-4B78-420D-960E-EC903A05B13EQ34171352-EB0566C6-DA2F-4DA1-B1D8-98B724E58392Q34198760-C213261D-0285-442A-8CC6-DE73AFFBB0ABQ35121898-6C4E9A5A-5645-4012-B362-89A59DAB006FQ36489564-9E862A6E-EB92-4A3F-A8C1-7C5E8BBC1AF0Q36564557-E102F464-6A7B-408E-8C21-793BDCB28411Q39535319-B29412B9-B3C8-455F-A94E-0B4A4E98E060Q40310701-7FC933D8-3E1F-448E-B829-70BE3DCDC175Q42447413-3DEA6B44-403F-457C-8112-6E2A7CE639F5Q46966972-1AD79DC5-6CBA-4B17-8C7E-4114C0787DFF
P2860
Proteolytic Cleavage of the Linker Region of the Human P-glycoprotein Modulates Its ATPase Function.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Proteolytic Cleavage of the Li ...... Modulates Its ATPase Function.
@en
Proteolytic Cleavage of the Li ...... Modulates Its ATPase Function.
@nl
type
label
Proteolytic Cleavage of the Li ...... Modulates Its ATPase Function.
@en
Proteolytic Cleavage of the Li ...... Modulates Its ATPase Function.
@nl
prefLabel
Proteolytic Cleavage of the Li ...... Modulates Its ATPase Function.
@en
Proteolytic Cleavage of the Li ...... Modulates Its ATPase Function.
@nl
P2860
P356
P1476
Proteolytic Cleavage of the Li ...... Modulates Its ATPase Function.
@en
P2093
Shanthy L Nuti
U Subrahmanyeswara Rao
P2860
P304
29417-29423
P356
10.1074/JBC.M204054200
P407
P577
2002-06-07T00:00:00Z