Endocytic trafficking of activated EGFR is AP-2 dependent and occurs through preformed clathrin spots.
about
Threshold-controlled ubiquitination of the EGFR directs receptor fateEGF receptor trafficking: consequences for signaling and cancerSingle Particle Tracking Reveals that EGFR Signaling Activity Is Amplified in Clathrin-Coated PitsGoverning epidermal homeostasis by coupling cell-cell adhesion to integrin and growth factor signaling, proliferation, and apoptosisEndocytosis and signalling: intertwining molecular networksReal-time fluorescence imaging with 20 nm axial resolution.EGFR oligomerization organizes kinase-active dimers into competent signalling platformsMultiple mechanisms collectively regulate clathrin-mediated endocytosis of the epidermal growth factor receptor.Adaptor protein complexes and intracellular transport.New and recurrent AAGAB mutations in punctate palmoplantar keratoderma.Imaging single endocytic events reveals diversity in clathrin, dynamin and vesicle dynamics.Internalization of the TGF-β type I receptor into caveolin-1 and EEA1 double-positive early endosomesQuantitative analysis of gradient sensing: towards building predictive models of chemotaxis in cancer.Hierarchical classification strategy for Phenotype extraction from epidermal growth factor receptor endocytosis screening.A systematic analysis reveals heterogeneous changes in the endocytic activities of cancer cells.Regulation of fibroblast growth factor receptor signalling and trafficking by Src and Eps8Sorting it out in endosomes: an emerging concept in renal epithelial cell transport regulation.Haploinsufficiency for AAGAB causes clinically heterogeneous forms of punctate palmoplantar keratoderma.Genome-wide co-localization of active EGFR and downstream ERK pathway kinases mirrors mitogen-inducible RNA polymerase 2 genomic occupancy.Endocytosis and signaling: cell logistics shape the eukaryotic cell plan.Human leucine-rich repeat kinase 1 and 2: intersecting or unrelated functions?Review series: From uncertain beginnings: initiation mechanisms of clathrin-mediated endocytosis.Distinct Temporal Regulation of RET Isoform Internalization: Roles of Clathrin and AP2.USP17 is required for clathrin mediated endocytosis of epidermal growth factor receptor.Polarised clathrin-mediated endocytosis of EGFR during chemotactic invasion.Proteomic analysis of the epidermal growth factor receptor (EGFR) interactome and post-translational modifications associated with receptor endocytosis in response to EGF and stress.Cellular entry of nanoparticles via serum sensitive clathrin-mediated endocytosis, and plasma membrane permeabilization.Ligand-induced EGF receptor oligomerization is kinase-dependent and enhances internalization.Nbr1 is a novel inhibitor of ligand-mediated receptor tyrosine kinase degradation.Heterozygous mutations in AAGAB cause type 1 punctate palmoplantar keratoderma with evidence for increased growth factor signaling.The clathrin adaptor complex AP-2 mediates endocytosis of brassinosteroid insensitive1 in Arabidopsis.Sortilin limits EGFR signaling by promoting its internalization in lung cancer.Selective regulation of clathrin-mediated epidermal growth factor receptor signaling and endocytosis by phospholipase C and calcium.Measurement of Epidermal Growth Factor Receptor-Derived Signals Within Plasma Membrane Clathrin Structures.The EGFR odyssey - from activation to destruction in space and time.IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling.Receptor Tyrosine Kinase Ubiquitination and De-Ubiquitination in Signal Transduction and Receptor Trafficking.Annexins-Coordinators of Cholesterol Homeostasis in Endocytic Pathways.Differential roles of Grb2 and AP-2 in p38 MAPK- and EGF-induced EGFR internalization.LRBA in the endomembrane system
P2860
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P2860
Endocytic trafficking of activated EGFR is AP-2 dependent and occurs through preformed clathrin spots.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Endocytic trafficking of activ ...... ough preformed clathrin spots.
@en
Endocytic trafficking of activ ...... ough preformed clathrin spots.
@nl
type
label
Endocytic trafficking of activ ...... ough preformed clathrin spots.
@en
Endocytic trafficking of activ ...... ough preformed clathrin spots.
@nl
prefLabel
Endocytic trafficking of activ ...... ough preformed clathrin spots.
@en
Endocytic trafficking of activ ...... ough preformed clathrin spots.
@nl
P2860
P356
P1476
Endocytic trafficking of activ ...... ough preformed clathrin spots.
@en
P2093
Joshua Z Rappoport
P2860
P304
P356
10.1242/JCS.040030
P407
P577
2009-04-07T00:00:00Z