S0859, an N-cyanosulphonamide inhibitor of sodium-bicarbonate cotransport in the heart.
about
Regulators of Slc4 bicarbonate transporter activityQuantification of carbonic anhydrase gene expression in ventricle of hypertrophic and failing human heartThe divergence, actions, roles, and relatives of sodium-coupled bicarbonate transportersHuman Enteroids as a Model of Upper Small Intestinal Ion Transport Physiology and Pathophysiology.Isoflurane protects cardiomyocytes and mitochondria by immediate and cytosol-independent action at reperfusion.NBCe1 as a model carrier for understanding the structure-function properties of Na⁺ -coupled SLC4 transporters in health and disease.Effect of nitric oxide donors S-nitroso-N-acetyl-DL-penicillamine, spermine NONOate and propylamine propylamine NONOate on intracellular pH in cardiomyocytesAutocrine boost of NMDAR current in hippocampal CA1 pyramidal neurons by a PMCA-dependent, perisynaptic, extracellular pH shiftInfluence of pH on Ca²⁺ current and its control of electrical and Ca²⁺ signaling in ventricular myocytes.Antibodies against the cardiac sodium/bicarbonate co-transporter (NBCe1) as pharmacological tools.Bicarbonate Increases Ischemia-Reperfusion Damage by Inhibiting MitophagyCation-coupled bicarbonate transportersModulation of the cardiac sodium/bicarbonate cotransporter by the renin angiotensin aldosterone system: pathophysiological consequences.Regulation of the cardiac sodium/bicarbonate cotransporter by angiotensin II: potential Contribution to structural, ionic and electrophysiological myocardial remodelling.Structure, function, and regulation of the SLC4 NBCe1 transporter and its role in causing proximal renal tubular acidosis.Proximal renal tubular acidosis mediated by mutations in NBCe1-A: unraveling the transporter's structure-functional properties.SLC4A transportersNBCe1 mediates the acute stimulation of astrocytic glycolysis by extracellular K+Negative News: Cl- and HCO3- in the Vascular Wall.The Role of pH Regulation in Cancer Progression.Binding of carbonic anhydrase IX to extracellular loop 4 of the NBCe1 Na+/HCO3- cotransporter enhances NBCe1-mediated HCO3- influx in the rat heart.HCO(3)(-)-independent conductance with a mutant Na(+)/HCO(3)(-) cotransporter (SLC4A4) in a case of proximal renal tubular acidosis with hypokalaemic paralysis.Dual role of CO2/HCO3(-) buffer in the regulation of intracellular pH of three-dimensional tumor growths.Goblet Cell Hyperplasia Requires High Bicarbonate Transport To Support Mucin Release.Mechanisms of CO2/H+ Sensitivity of Astrocytes.Facilitation by intracellular carbonic anhydrase of Na+ -HCO3- co-transport but not Na+ / H+ exchange activity in the mammalian ventricular myocyte.The N-terminal cytoplasmic region of NCBE displays features of an intrinsic disordered structure and represents a novel target for specific drug screening.Blowing off acid: a new tool to study Na+/HCO3- co-transport.Spatial regulation of intracellular pH in multicellular strands of neonatal rat cardiomyocytes.Elevated carbon dioxide upregulates NBCn1 Na+/HCO3(-) cotransporter in human embryonic kidney cells.The Na+/HCO3- co-transporter is protective during ischemia in astrocytes.Reversed electrogenic sodium bicarbonate cotransporter 1 is the major acid loader during recovery from cytosolic alkalosis in mouse cortical astrocytes.Na+,HCO3- -cotransport is functionally upregulated during human breast carcinogenesis and required for the inverted pH gradient across the plasma membrane.SLC4A7 sodium bicarbonate co-transporter controls mitochondrial apoptosis in ischaemic coronary endothelial cells.CFTR/ENaC dependent regulation of membrane potential during human sperm capacitation is initiated by bicarbonate uptake through NBC.WNK1 kinase and its partners Akt, SGK1 and NBC-family Na+/HCO3- cotransporters are potential therapeutic targets for glioblastoma stem-like cells linked to Bisacodyl signaling.Molecular Basis and Differentiation-Associated Alterations of Anion Secretion in Human Duodenal Enteroid Monolayers.Synthesis of N-cyano-substituted sulfilimine and sulfoximine derivatives of S0859 and their biological evaluation as sodium bicarbonate co-transport inhibitors
P2860
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P2860
S0859, an N-cyanosulphonamide inhibitor of sodium-bicarbonate cotransport in the heart.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
S0859, an N-cyanosulphonamide inhibitor of sodium-bicarbonate cotransport in the heart.
@en
S0859, an N-cyanosulphonamide inhibitor of sodium-bicarbonate cotransport in the heart.
@nl
type
label
S0859, an N-cyanosulphonamide inhibitor of sodium-bicarbonate cotransport in the heart.
@en
S0859, an N-cyanosulphonamide inhibitor of sodium-bicarbonate cotransport in the heart.
@nl
prefLabel
S0859, an N-cyanosulphonamide inhibitor of sodium-bicarbonate cotransport in the heart.
@en
S0859, an N-cyanosulphonamide inhibitor of sodium-bicarbonate cotransport in the heart.
@nl
P2093
P2860
P356
P1476
S0859, an N-cyanosulphonamide inhibitor of sodium-bicarbonate cotransport in the heart
@en
P2093
F F-T Ch'en
P M Cobden
R D Vaughan-Jones
P2860
P304
P356
10.1038/SJ.BJP.0707667
P407
P577
2008-01-21T00:00:00Z