Ethoxyquin-induced resistance to aflatoxin B1 in the rat is associated with the expression of a novel alpha-class glutathione S-transferase subunit, Yc2, which possesses high catalytic activity for aflatoxin B1-8,9-epoxide.
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Molecular cloning, expression and catalytic activity of a human AKR7 member of the aldo-keto reductase superfamily: evidence that the major 2-carboxybenzaldehyde reductase from human liver is a homologue of rat aflatoxin B1-aldehyde reductaseMolecular cloning and heterologous expression of a cDNA encoding a mouse glutathione S-transferase Yc subunit possessing high catalytic activity for aflatoxin B1-8,9-epoxideDeterminants of specificity for aflatoxin B1-8,9-epoxide in alpha-class glutathione S-transferasesRegulation of aflatoxin B1-metabolizing aldehyde reductase and glutathione S-transferase by chemoprotectorsCharacterization of the rat glutathione S-transferase Yc2 subunit gene, GSTA5: identification of a putative antioxidant-responsive element in the 5'-flanking region of rat GSTA5 that may mediate chemoprotection against aflatoxin B1Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative diseaseAn ethoxyquin-inducible aldehyde reductase from rat liver that metabolizes aflatoxin B1 defines a subfamily of aldo-keto reductasesIsoenzyme-specific up-regulation of glutathione transferase and aldo-keto reductase mRNA expression by dietary quercetin in rat liverA proteomic analysis of thioacetamide-induced hepatotoxicity and cirrhosis in rat livers.Modeling the chemoprotective functions of glutathione S-transferases in cultured cell lines by heterologous expression.Interspecies differences in cancer susceptibility and toxicity.Sulforaphane, a cancer chemopreventive agent, induces pathways associated with membrane biosynthesis in response to tissue damage by aflatoxin B1.Effect of cadmium on glutathione S-transferase and metallothionein gene expression in coho salmon liver, gill and olfactory tissues.A novel aldehyde reductase with activity towards a metabolite of aflatoxin B1 is expressed in rat liver during carcinogenesis and following the administration of an anti-oxidant.Glutathione S-transferase Yc cDNA from Syrian hamster kidney.Bioactivation and Regioselectivity of Pig Cytochrome P450 3A29 towards Aflatoxin B₁.Mechanisms of induction of cytosolic and microsomal glutathione transferase (GST) genes by xenobiotics and pro-inflammatory agents.Effects of hyperbilirubinaemia on glutathione S-transferase isoenzymes in cerebellar cortex of the Gunn ratThe characterization of glutathione S-transferases from rat olfactory epithelium.Growth hormone- and testosterone-dependent regulation of glutathione transferase subunit A5 in rat liver.Constitutive and inducible profile of glutathione S-transferase subunits in biliary epithelial cells and hepatocytes isolated from rat liver.Chlorambucil-monoglutathionyl conjugate is sequestered by human alpha class glutathione S-transferases.Mass spectrometric analysis of rat liver cytosolic glutathione S-transferases: modifications are limited to N-terminal processing.Variability of glutathione S-transferase isoenzyme patterns in matched normal and cancer human breast tissue.Purification from rat liver of a novel constitutively expressed member of the aldo-keto reductase 7 family that is widely distributed in extrahepatic tissues.Repeated administration of oxycodone modifies the gene expression of several drug metabolising enzymes in the hepatic tissue of male Sprague-Dawley rats, including glutathione S-transferase A-5 (rGSTA5) and CYP3A2.A sulforaphane analogue that potently activates the Nrf2-dependent detoxification pathway.Characterisation of a novel mouse liver aldo-keto reductase AKR7A5.Modulation of glutathione S-transferase alpha by hepatitis B virus and the chemopreventive drug oltipraz.Opinion of the scientific panel on contaminants in the food chain [CONTAM] related to the potential increase of consumer health risk by a possible increase of the existing maximum levels for aflatoxins in almonds, hazelnuts and pistachios and deri...Tissue and species distribution of the glutathione pathway transcriptome.Aflatoxins in aquatic species: metabolism, toxicity and perspectives
P2860
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P2860
Ethoxyquin-induced resistance to aflatoxin B1 in the rat is associated with the expression of a novel alpha-class glutathione S-transferase subunit, Yc2, which possesses high catalytic activity for aflatoxin B1-8,9-epoxide.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年学术文章
@wuu
1991年学术文章
@zh-cn
1991年学术文章
@zh-hans
1991年学术文章
@zh-my
1991年学术文章
@zh-sg
1991年學術文章
@yue
1991年學術文章
@zh
1991年學術文章
@zh-hant
name
Ethoxyquin-induced resistance ...... for aflatoxin B1-8,9-epoxide.
@en
Ethoxyquin-induced resistance ...... for aflatoxin B1-8,9-epoxide.
@nl
type
label
Ethoxyquin-induced resistance ...... for aflatoxin B1-8,9-epoxide.
@en
Ethoxyquin-induced resistance ...... for aflatoxin B1-8,9-epoxide.
@nl
prefLabel
Ethoxyquin-induced resistance ...... for aflatoxin B1-8,9-epoxide.
@en
Ethoxyquin-induced resistance ...... for aflatoxin B1-8,9-epoxide.
@nl
P2093
P2860
P356
P1433
P1476
Ethoxyquin-induced resistance ...... for aflatoxin B1-8,9-epoxide.
@en
P2093
P2860
P304
P356
10.1042/BJ2790385
P407
P478
279 ( Pt 2)
P577
1991-10-01T00:00:00Z