Inhibitory effects of ZSTK474, a novel phosphoinositide 3-kinase inhibitor, on osteoclasts and collagen-induced arthritis in mice - Wikidata - wikimedia - TriplyDB

Inhibitory effects of ZSTK474, a novel phosphoinositide 3-kinase inhibitor, on osteoclasts and collagen-induced arthritis in mice

Inhibitory effects of ZSTK474, a novel phosphoinositide 3-kinase inhibitor, on osteoclasts and collagen-induced arthritis in mice

http://www.wikidata.org/entity/Q42077222

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Class I PI3K inhibitor ZSTK474 mediates a shift in microglial/macrophage phenotype and inhibits inflammatory response in mice with cerebral ischemia/reperfusion injury.Anti-Inflammatory Effects and Joint Protection in Collagen-Induced Arthritis after Treatment with IQ-1S, a Selective c-Jun N-Terminal Kinase Inhibitor.The Therapeutic Potential for PI3K Inhibitors in Autoimmune Rheumatic Diseases Program Death-1 Suppresses Autoimmune Arthritis by Inhibiting Th17 Response.Btk inhibition suppresses agonist-induced human macrophage activation and inflammatory gene expression in RA synovial tissue explants.IL-17 in the rheumatologist's line of sight.Extended treatment with selective phosphatidylinositol 3-kinase and mTOR inhibitors has effects on metabolism, growth, behaviour and bone strength.In vitro antimetastatic effect of phosphatidylinositol 3-kinase inhibitor ZSTK474 on prostate cancer PC3 cells.Kinase inhibitors of the IGF-1R as a potential therapeutic agent for rheumatoid arthritis.ZSTK474, a novel PI3K inhibitor, modulates human CD14+ monocyte-derived dendritic cell functions and suppresses experimental autoimmune encephalomyelitis.Class IA phosphatidylinositol 3-kinase regulates osteoclastic bone resorption through protein kinase B-mediated vesicle transport.Inhibitory effects of ZSTK474, a phosphatidylinositol 3-kinase inhibitor, on adjuvant-induced arthritis in rats.

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Inhibitory effects of ZSTK474, a novel phosphoinositide 3-kinase inhibitor, on osteoclasts and collagen-induced arthritis in mice

http://www.wikidata.org/entity/Q42077222

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2010 nî lūn-bûn

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2010年の論文

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年學術文章

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Inhibitory effects of ZSTK474, ...... agen-induced arthritis in mice

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Inhibitory effects of ZSTK474, ...... agen-induced arthritis in mice

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Inhibitory effects of ZSTK474, ...... agen-induced arthritis in mice

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Inhibitory effects of ZSTK474, ...... agen-induced arthritis in mice

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Inhibitory effects of ZSTK474, ...... agen-induced arthritis in mice

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Arthritis Research and Therapy

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Inhibitory effects of ZSTK474, ...... agen-induced arthritis in mice

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Kazuhiko Haruta

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Naoto Tamura

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Shigeyuki Mori

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Shoko Toyama

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Takao Yamori

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Takeo Karakida

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Tetsuo Watanabe

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Yoshinari Takasaki

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P2860

PI3K delta and PI3K gamma: partners in crime in inflammation in rheumatoid arthritis and beyond?

The molecular scaffold Gab2 is a crucial component of RANK signaling and osteoclastogenesis

Increased interleukin-17 production via a phosphoinositide 3-kinase/Akt and nuclear factor kappaB-dependent pathway in patients with rheumatoid arthritis

PI3Kgamma inhibition: towards an 'aspirin of the 21st century'?

RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesis

Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems

SHIP-deficient mice are severely osteoporotic due to increased numbers of hyper-resorptive osteoclasts

Molecular pharmacology and antitumor activity of PX-866, a novel inhibitor of phosphoinositide-3-kinase signaling

Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts

Evidence for a functional association between phosphatidylinositol 3-kinase and c-src in the spreading response of osteoclasts to colony-stimulating factor-1.

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