Splicing variation of Long-IRBIT determines the target selectivity of IRBIT family proteins.

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Consensus report of the 8 and 9th Weinman Symposia on Gene x Environment Interaction in carcinogenesis: novel opportunities for precision medicine

P2860

Q57461758-22A7761E-C727-4652-ADA8-FD10A36AF496

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Splicing variation of Long-IRBIT determines the target selectivity of IRBIT family proteins.

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2017 nî lūn-bûn

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2017年の論文

@ja

2017年論文

@yue

2017年論文

@zh-hant

2017年論文

@zh-hk

2017年論文

@zh-mo

2017年論文

@zh-tw

2017年论文

@wuu

2017年论文

@zh

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name

Splicing variation of Long-IRB ...... vity of IRBIT family proteins.

@en

Splicing variation of Long-IRB ...... vity of IRBIT family proteins.

@nl

type

Item

label

Splicing variation of Long-IRB ...... vity of IRBIT family proteins.

@en

Splicing variation of Long-IRB ...... vity of IRBIT family proteins.

@nl

prefLabel

Splicing variation of Long-IRB ...... vity of IRBIT family proteins.

@en

Splicing variation of Long-IRB ...... vity of IRBIT family proteins.

@nl

P1476

Splicing variation of Long-IRB ...... ivity of IRBIT family proteins

@en

P2093

Akihiro Mizutani

http://www.w3.org/2001/XMLSchema#string

George Seki

http://www.w3.org/2001/XMLSchema#string

Hideaki Ando

http://www.w3.org/2001/XMLSchema#string

Hideomi Yamada

http://www.w3.org/2001/XMLSchema#string

Katsuhiko Mikoshiba

http://www.w3.org/2001/XMLSchema#string

Matsumi Hirose

http://www.w3.org/2001/XMLSchema#string

Naoko Ogawa

http://www.w3.org/2001/XMLSchema#string

P2860

IRBIT, an inositol 1,4,5-trisphosphate receptor-binding protein, specifically binds to and activates pancreas-type Na+/HCO3- cotransporter 1 (pNBC1)

IRBIT suppresses IP3 receptor activity by competing with IP3 for the common binding site on the IP3 receptor

An IRBIT homologue lacks binding activity to inositol 1,4,5-trisphosphate receptor due to the unique N-terminal appendage

Inositol 1,4,5-triphosphate receptor-binding protein released with inositol 1,4,5-triphosphate (IRBIT) associates with components of the mRNA 3' processing machinery in a phosphorylation-dependent manner and inhibits polyadenylation

IRBIT, inositol 1,4,5-triphosphate (IP3) receptor-binding protein released with IP3, binds Na+/H+ exchanger NHE3 and activates NHE3 activity in response to calcium

Activation of Na+/H+ exchanger NHE3 by angiotensin II is mediated by inositol 1,4,5-triphosphate (IP3) receptor-binding protein released with IP3 (IRBIT) and Ca2+/calmodulin-dependent protein kinase II

Defective membrane expression of the Na(+)-HCO(3)(-) cotransporter NBCe1 is associated with familial migraine

IRBIT, a novel inositol 1,4,5-trisphosphate (IP3) receptor-binding protein, is released from the IP3 receptor upon IP3 binding to the receptor

IRBIT coordinates epithelial fluid and HCO3- secretion by stimulating the transporters pNBC1 and CFTR in the murine pancreatic duct

IRBIT governs epithelial secretion in mice by antagonizing the WNK/SPAK kinase pathway

P304

3921-3926

http://www.w3.org/2001/XMLSchema#string

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scholarly article

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10.1073/PNAS.1618514114

http://www.w3.org/2001/XMLSchema#string

P407

English

P433

http://www.w3.org/2001/XMLSchema#string

P478

114

http://www.w3.org/2001/XMLSchema#string

P50

Nobuhiko Satoh

Katsuhiro Kawaai

Benjamin Bonneau

P577

2017-03-27T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

28348216

http://www.w3.org/2001/XMLSchema#string

P932

5393198

http://www.w3.org/2001/XMLSchema#string

Splicing variation of Long-IRBIT determines the target selectivity of IRBIT family proteins.

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P2860

P2860

Splicing variation of Long-IRBIT determines the target selectivity of IRBIT family proteins.

description

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type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932