Ligand-binding domain determines endoplasmic reticulum exit of AMPA receptors
about
Pharmacological chaperoning: a primer on mechanism and pharmacologyAMPA-receptor specific biogenesis complexes control synaptic transmission and intellectual ability.Autoinactivation of the stargazin-AMPA receptor complex: subunit-dependency and independence from physical dissociation.Neuronal gamma-aminobutyric acid (GABA) type A receptors undergo cognate ligand chaperoning in the endoplasmic reticulum by endogenous GABA.Glutamate binding to the GluN2B subunit controls surface trafficking of N-methyl-D-aspartate (NMDA) receptorsCysteine 893 is a target of regulatory thiol modifications of GluA1 AMPA receptors.AMPA GluA1-flip targeted oligonucleotide therapy reduces neonatal seizures and hyperexcitabilityActivity-regulated RNA editing in select neuronal subfields in hippocampus.Agonist binding to the GluK5 subunit is sufficient for functional surface expression of heteromeric GluK2/GluK5 kainate receptors.Mechanistic Insight into NMDA Receptor Dysregulation by Rare Variants in the GluN2A and GluN2B Agonist Binding Domains.Assembly of AMPA receptors: mechanisms and regulation.Mapping the interaction sites between AMPA receptors and TARPs reveals a role for the receptor N-terminal domain in channel gating.The N-terminal domain modulates α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor desensitization.Aggregation Limits Surface Expression of Homomeric GluA3 Receptors.Activity-mediated AMPA receptor remodeling, driven by alternative splicing in the ligand-binding domainCognate Ligand Chaperoning: a Novel Mechanism for the Post-translational Regulation of Neurotransmitter Receptor Biogenesis.Pharmacological Chaperones: Beyond Conformational Disorders.Mechanisms of CPT1C-Dependent AMPAR Trafficking Enhancement
P2860
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P2860
Ligand-binding domain determines endoplasmic reticulum exit of AMPA receptors
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Ligand-binding domain determines endoplasmic reticulum exit of AMPA receptors
@en
Ligand-binding domain determines endoplasmic reticulum exit of AMPA receptors
@nl
type
label
Ligand-binding domain determines endoplasmic reticulum exit of AMPA receptors
@en
Ligand-binding domain determines endoplasmic reticulum exit of AMPA receptors
@nl
prefLabel
Ligand-binding domain determines endoplasmic reticulum exit of AMPA receptors
@en
Ligand-binding domain determines endoplasmic reticulum exit of AMPA receptors
@nl
P2093
P2860
P50
P356
P1476
Ligand-binding domain determines endoplasmic reticulum exit of AMPA receptors
@en
P2093
Kari Keinänen
Sami Hinkkuri
Tommi Möykkynen
P2860
P304
36032-36039
P356
10.1074/JBC.M110.156943
P407
P577
2010-09-13T00:00:00Z