Interferon regulatory factor 3 attenuates reovirus myocarditis and contributes to viral clearance.
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Diminished reovirus capsid stability alters disease pathogenesis and littermate transmissionThe early interferon response to rotavirus is regulated by PKR and depends on MAVS/IPS-1, RIG-I, MDA-5, and IRF3.The proapoptotic Bcl-2 protein Bax plays an important role in the pathogenesis of reovirus encephalitisType I interferon signaling limits reoviral tropism within the brain and prevents lethal systemic infectionA single-amino-acid polymorphism in reovirus protein μ2 determines repression of interferon signaling and modulates myocarditisReovirus activates a caspase-independent cell death pathway.An ITAM in a nonenveloped virus regulates activation of NF-κB, induction of beta interferon, and viral spread.Viral myocarditis: from experimental models to molecular diagnosis in patients.Role of innate and adaptive immune mechanisms in cardiac injury and repair.Viral RNA at Two Stages of Reovirus Infection Is Required for the Induction of Necroptosis.NF-κB activation is cell type-specific in the heart.Apoptosis induced by mammalian reovirus is beta interferon (IFN) independent and enhanced by IFN regulatory factor 3- and NF-κB-dependent expression of Noxa.Reovirus inhibits interferon production by sequestering IRF3 into viral factories.Spontaneous activation of a MAVS-dependent antiviral signaling pathway determines high basal interferon-β expression in cardiac myocytes.Differential delivery of genomic dsRNA causes reovirus strain-specific differences in IRF3 activation.Current understanding of reovirus oncolysis mechanisms.Reovirus infection induces stabilization and up-regulation of cellular transcripts that encode regulators of TGF-β signaling
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Interferon regulatory factor 3 attenuates reovirus myocarditis and contributes to viral clearance.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Interferon regulatory factor 3 ...... ontributes to viral clearance.
@en
Interferon regulatory factor 3 ...... ontributes to viral clearance.
@nl
type
label
Interferon regulatory factor 3 ...... ontributes to viral clearance.
@en
Interferon regulatory factor 3 ...... ontributes to viral clearance.
@nl
prefLabel
Interferon regulatory factor 3 ...... ontributes to viral clearance.
@en
Interferon regulatory factor 3 ...... ontributes to viral clearance.
@nl
P2093
P2860
P356
P1433
P1476
Interferon regulatory factor 3 ...... ontributes to viral clearance.
@en
P2093
Barbara Sherry
Geoffrey H Holm
Terence S Dermody
P2860
P304
P356
10.1128/JVI.01742-09
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P577
2010-05-12T00:00:00Z