Dysregulation of glutathione synthesis during cholestasis in mice: molecular mechanisms and therapeutic implications - Wikidata - wikimedia - TriplyDB

Dysregulation of glutathione synthesis during cholestasis in mice: molecular mechanisms and therapeutic implications

Dysregulation of glutathione synthesis during cholestasis in mice: molecular mechanisms and therapeutic implications

http://www.wikidata.org/entity/Q42099362

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Primary biliary cirrhosis: From bench to bedside Glutathione synthesis Essential role of PH domain and leucine-rich repeat protein phosphatase 2 in Nrf2 suppression via modulation of Akt/GSK3β/Fyn kinase axis during oxidative hepatocellular toxicity Oral methylthioadenosine administration attenuates fibrosis and chronic liver disease progression in Mdr2-/- mice Mechanism and significance of changes in glutamate-cysteine ligase expression during hepatic fibrogenesis Metabolomics Coupled with Multivariate Data and Pathway Analysis on Potential Biomarkers in Cholestasis and Intervention Effect of Paeonia lactiflora Pall.Effects of reduced glutathione therapy on chronic hepatitis B.S-adenosylmethionine regulates dual-specificity mitogen-activated protein kinase phosphatase expression in mouse and human hepatocytes.S-adenosylmethionine in liver health, injury, and cancer.Participation of nuclear factor (erythroid 2-related), factor 2 in ameliorating lithocholic acid-induced cholestatic liver injury in mice.Activation of a novel c-Myc-miR27-prohibitin 1 circuitry in cholestatic liver injury inhibits glutathione synthesis in mice.Protective Effects of Norursodeoxycholic Acid Versus Ursodeoxycholic Acid on Thioacetamide-induced Rat Liver Fibrosis S-adenosyl-L-methionine for the treatment of chronic liver disease: a systematic review and meta-analysis.Glyphosate, pathways to modern diseases III: Manganese, neurological diseases, and associated pathologies.Nuclear factor-E2-related factor 2 is a major determinant of bile acid homeostasis in the liver and intestine.Paeonia lactiflora Pall. protects against ANIT-induced cholestasis by activating Nrf2 via PI3K/Akt signaling pathway.The plasma S-adenosylmethionine level is associated with the severity of hepatitis B-related liver disease Suppression in PHLPP2 induction by morin promotes Nrf2-regulated cellular defenses against oxidative injury to primary rat hepatocytes.Targeting of Gamma-Glutamyl-Cysteine Ligase by miR-433 Reduces Glutathione Biosynthesis and Promotes TGF-β-Dependent Fibrogenesis.The NRF2-heme oxygenase-1 system modulates cyclosporin A-induced epithelial-mesenchymal transition and renal fibrosis.Protective Effects of Guava Pulp on Cholestatic Liver Injury Methionine adenosyltransferase 2B, HuR, and sirtuin 1 protein cross-talk impacts on the effect of resveratrol on apoptosis and growth in liver cancer cells.Possible Involvement of Nitric Oxide in Enhanced Liver Injury and Fibrogenesis during Cholestasis in Cytoglobin-deficient Mice.Oxidative stress: a systemic factor implicated in the pathogenesis of hepatic encephalopathy.How do nutritional antioxidants really work: nucleophilic tone and para-hormesis versus free radical scavenging in vivo Dioscin Protects ANIT-Induced Intrahepatic Cholestasis Through Regulating Transporters, Apoptosis and Oxidative Stress.Induction of avian musculoaponeurotic fibrosarcoma proteins by toxic bile acid inhibits expression of glutathione synthetic enzymes and contributes to cholestatic liver injury in mice.Redox homeostasis: The Golden Mean of healthy living.Deregulated methionine adenosyltransferase α1, c-Myc, and Maf proteins together promote cholangiocarcinoma growth in mice and humans(‡).Fish omega-3 fatty acids induce liver fibrosis in the treatment of bile duct-ligated rats.Paeoniflorin ameliorates ANIT-induced cholestasis by activating Nrf2 through an PI3K/Akt-dependent pathway in rats.Morin mitigates acetaminophen-induced liver injury by potentiating Nrf2 regulated survival mechanism through molecular intervention in PHLPP2-Akt-Gsk3β axis.S-Adenosylmethionine Attenuates Oxidative Stress and Neuroinflammation Induced by Amyloid-β Through Modulation of Glutathione Metabolism.Protective Effects of Alisol B 23-Acetate Via Farnesoid X Receptor-Mediated Regulation of Transporters and Enzymes in Estrogen-Induced Cholestatic Liver Injury in Mice.Protective effects of alisol B 23-acetate from edible botanical Rhizoma alismatis against carbon tetrachloride-induced hepatotoxicity in mice.Yinzhihuang attenuates ANIT-induced intrahepatic cholestasis in rats through upregulation of Mrp2 and Bsep expressions.Yinchenhao Decoction Ameliorates Alpha-Naphthylisothiocyanate Induced Intrahepatic Cholestasis in Rats by Regulating Phase II Metabolic Enzymes and Transporters.Mechanisms of MAFG Dysregulation in Cholestatic Liver Injury and Development of Liver Cancer

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Dysregulation of glutathione synthesis during cholestasis in mice: molecular mechanisms and therapeutic implications

http://www.wikidata.org/entity/Q42099362

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Dysregulation of glutathione s ...... s and therapeutic implications

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Dysregulation of glutathione s ...... s and therapeutic implications

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Dysregulation of glutathione s ...... s and therapeutic implications

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Dysregulation of glutathione s ...... s and therapeutic implications

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Dysregulation of glutathione s ...... s and therapeutic implications

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Heping Yang

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Jiaping Li

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Komal Ramani

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Kwang Suk Ko

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Meng Xia

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Pilsoo Oh

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Shelly C Lu

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Tony W H Li

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P2860

Genome-wide association scan identifies candidate polymorphisms associated with differential response to anti-TNF treatment in rheumatoid arthritis

Small maf (MafG and MafK) proteins negatively regulate antioxidant response element-mediated expression and antioxidant induction of the NAD(P)H:Quinone oxidoreductase1 gene

c-Maf negatively regulates ARE-mediated detoxifying enzyme genes expression and anti-oxidant induction

Nrf1 is targeted to the endoplasmic reticulum membrane by an N-terminal transmembrane domain. Inhibition of nuclear translocation and transacting function

Nrf1 and Nrf2 regulate rat glutamate-cysteine ligase catalytic subunit transcription indirectly via NF-kappaB and AP-1

Ursodeoxycholic acid protects hepatocytes against oxidative injury via induction of antioxidants

Tumour necrosis factor alpha induces co-ordinated activation of rat GSH synthetic enzymes via nuclear factor kappaB and activator protein-1

Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway

Use of ursodeoxycholic acid in liver diseases.

Changes in S-adenosylmethionine and GSH homeostasis during endotoxemia in mice.

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