Selectivity and specificity of sphingosine-1-phosphate receptor ligands: caveats and critical thinking in characterizing receptor-mediated effects.
about
Sphingosine 1-phosphate enhances the excitability of rat sensory neurons through activation of sphingosine 1-phosphate receptors 1 and/or 3Dendritic cell sphingosine 1-phosphate receptor-3 regulates Th1-Th2 polarity in kidney ischemia-reperfusion injury.An update on the biology of sphingosine 1-phosphate receptors.Targeting the sphingosine-1-phosphate axis in cancer, inflammation and beyond.The involvement of high mobility group 1 cytokine and phospholipases A2 in diabetic retinopathy.Influence of the hypothalamic arcuate nucleus on intraocular pressure and the role of opioid peptidesSphingosine-1-phosphate receptor 2Regulation of mammalian physiology, development, and disease by the sphingosine 1-phosphate and lysophosphatidic acid receptors.Antitumor Activity of a Novel Sphingosine-1-Phosphate 2 Antagonist, AB1, in Neuroblastoma.Hydrophobic bile acid apoptosis is regulated by sphingosine-1-phosphate receptor 2 in rat hepatocytes and human hepatocellular carcinoma cells.Pharmacologic manipulation of conventional outflow facility in ex vivo mouse eyesSphingosine 1-phosphate receptor 2 antagonist JTE-013 increases the excitability of sensory neurons independently of the receptor.Expression of S1P metabolizing enzymes and receptors correlate with survival time and regulate cell migration in glioblastoma multiforme.Sphingosine-1-phosphate receptor 3 influences cell cycle progression in muscle satellite cells.Vascular transcriptome profiling identifies Sphingosine kinase 1 as a modulator of angiotensin II-induced vascular dysfunction.Neurotoxicity of acrylamide in exposed workersS1P(4) receptor mediates S1P-induced vasoconstriction in normotensive and hypertensive rat lungs.Sphingosine-1-phosphate receptor 3 promotes leukocyte rolling by mobilizing endothelial P-selectin.Induction of chemokine (C-C motif) ligand 2 by sphingosine-1-phosphate signaling in neuroblastoma.Selectivity and specificity of sphingosine 1-phosphate receptor ligands: "off-targets" or complex pharmacology?Sphingosine 1-phosphate (S1P) induces S1P2 receptor-dependent tonic contraction in murine iliac lymph vessels.Uridine adenosine tetraphosphate acts as a proangiogenic factor in vitro through purinergic P2Y receptors.Antagonism of sphingosine 1-phosphate receptor 2 causes a selective reduction of portal vein pressure in bile duct-ligated rodents.
P2860
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P2860
Selectivity and specificity of sphingosine-1-phosphate receptor ligands: caveats and critical thinking in characterizing receptor-mediated effects.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Selectivity and specificity of ...... ing receptor-mediated effects.
@en
Selectivity and specificity of ...... ing receptor-mediated effects.
@nl
type
label
Selectivity and specificity of ...... ing receptor-mediated effects.
@en
Selectivity and specificity of ...... ing receptor-mediated effects.
@nl
prefLabel
Selectivity and specificity of ...... ing receptor-mediated effects.
@en
Selectivity and specificity of ...... ing receptor-mediated effects.
@nl
P2860
P356
P1476
Selectivity and specificity of ...... ing receptor-mediated effects.
@en
P2860
P356
10.3389/FPHAR.2011.00009
P577
2011-02-22T00:00:00Z