Poly(A)-specific ribonuclease mediates 3'-end trimming of Argonaute2-cleaved precursor microRNAs.
about
Versatile microRNA biogenesis in animals and their virusesArgonaute-dependent small RNAs derived from single-stranded, non-structured precursorsMammalian PNLDC1 is a novel poly(A) specific exonuclease with discrete expression during early developmentPoly(A)-specific ribonuclease (PARN) mediates 3'-end maturation of the telomerase RNA componentMicrornas in prostate cancer: an overview.The influence of the 5΄-terminal nucleotide on AgoshRNA activity and biogenesis: importance of the polymerase III transcription initiation siteDeadenylation of mRNA by the CCR4-NOT complex in Drosophila: molecular and developmental aspects.Poly(A)-specific ribonuclease is a nuclear ribosome biogenesis factor involved in human 18S rRNA maturation.Eri1: a conserved enzyme at the crossroads of multiple RNA-processing pathways.PAPD5-mediated 3' adenylation and subsequent degradation of miR-21 is disrupted in proliferative disease.Exome sequencing links mutations in PARN and RTEL1 with familial pulmonary fibrosis and telomere shortening.eIF1A augments Ago2-mediated Dicer-independent miRNA biogenesis and RNA interference.TUT7 controls the fate of precursor microRNAs by using three different uridylation mechanisms.Destabilization of microRNAs in human cells by 3' deadenylation mediated by PARN and CUGBP1.Reciprocal inhibition between miR-26a and NF-κB regulates obesity-related chronic inflammation in chondrocytesRibozyme-enhanced single-stranded Ago2-processed interfering RNA triggers efficient gene silencing with fewer off-target effectsPARN deadenylase is involved in miRNA-dependent degradation of TP53 mRNA in mammalian cells.Biogenesis and regulation of the let-7 miRNAs and their functional implications.The RNase PARN-1 Trims piRNA 3' Ends to Promote Transcriptome Surveillance in C. elegans.Re-evaluation of the roles of DROSHA, Export in 5, and DICER in microRNA biogenesis.Identification and Functional Analysis of the Pre-piRNA 3' Trimmer in Silkworms.MicroRNA-33 suppresses CCL2 expression in chondrocytes.Guidelines for the optimal design of miRNA-based shRNAs.HER2-encoded mir-4728 forms a receptor-independent circuit with miR-21-5p through the non-canonical poly(A) polymerase PAPD5.Posttranscriptional manipulation of TERC reverses molecular hallmarks of telomere disease.Non-coding RNAs: An Introduction.Development of Novel Small Hairpin RNAs That do not Require Processing by Dicer or AGO2.Mechanistic insights on the Dicer-independent AGO2-mediated processing of AgoshRNAs.Toward optimization of AgoshRNA molecules that use a non-canonical RNAi pathway: variations in the top and bottom base pairs.DUSP11 - An RNA phosphatase that regulates host and viral non-coding RNAs in mammalian cells.Expanding the repertoire of deadenylases.MotomiRs: miRNAs in Motor Neuron Function and Disease.Comparison of preribosomal RNA processing pathways in yeast, plant and human cells - focus on coordinated action of endo- and exoribonucleases.Design, Characterization, and Lead Selection of Therapeutic miRNAs Targeting Huntingtin for Development of Gene Therapy for Huntington's Disease.An Ago2-associated capped transcriptional start site small RNA suppressing adenovirus DNA replication.Analysis of AgoshRNA maturation and loading into Ago2.Influence of the loop size and nucleotide composition on AgoshRNA biogenesis and activity.Silencing of HIV-1 by AgoshRNA molecules.Induced miR-99a expression represses Mtor cooperatively with miR-150 to promote regulatory T-cell differentiation.Deep Sequence Analysis of AgoshRNA Processing Reveals 3' A Addition and Trimming.
P2860
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P2860
Poly(A)-specific ribonuclease mediates 3'-end trimming of Argonaute2-cleaved precursor microRNAs.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Poly(A)-specific ribonuclease ...... 2-cleaved precursor microRNAs.
@en
type
label
Poly(A)-specific ribonuclease ...... 2-cleaved precursor microRNAs.
@en
prefLabel
Poly(A)-specific ribonuclease ...... 2-cleaved precursor microRNAs.
@en
P2093
P2860
P50
P1433
P1476
Poly(A)-specific ribonuclease ...... 2-cleaved precursor microRNAs.
@en
P2093
Antonio J Giraldez
Mayuko Yoda
Natsuko Izumi
Yuriko Sakaguchi
P2860
P304
P356
10.1016/J.CELREP.2013.09.029
P577
2013-10-24T00:00:00Z