Production of octaketide polyenes by the calicheamicin polyketide synthase CalE8: implications for the biosynthesis of enediyne core structures.
about
Polyketide synthase chemistry does not direct biosynthetic divergence between 9- and 10-membered enediynesSolution Structures of the Acyl Carrier Protein Domain from the Highly Reducing Type I Iterative Polyketide Synthase CalE8Structure-Guided Functional Characterization of Enediyne Self-Sacrifice Resistance Proteins, CalU16 and CalU19Manipulation of pathway regulation in Streptomyces globisporus for overproduction of the enediyne antitumor antibiotic C-1027.Natural products version 2.0: connecting genes to molecules.Biosynthetic genes and activity spectrum of antifungal polyynes from Collimonas fungivorans Ter331.Enediyne polyketide synthases stereoselectively reduce the β-ketoacyl intermediates to β-D-hydroxyacyl intermediates in enediyne core biosynthesis.New insights into the formation of fungal aromatic polyketides.Genome neighborhood network reveals insights into enediyne biosynthesis and facilitates prediction and prioritization for discovery.Crystal structure of SgcJ, an NTF2-like superfamily protein involved in biosynthesis of the nine-membered enediyne antitumor antibiotic C-1027Structural dynamics of a methionine γ-lyase for calicheamicin biosynthesis: Rotation of the conserved tyrosine stacking with pyridoxal phosphate.PKS and NRPS release mechanisms.Iterative type I polyketide synthases involved in enediyne natural product biosynthesis.Iterative polyketide biosynthesis by modular polyketide synthases in bacteria.Induced Chemical Defense of a Mushroom by a Double-Bond-Shifting Polyene Synthase.An Iterative Module in the Azalomycin F Polyketide Synthase Contains a Switchable Enoylreductase DomainEnvironmental control of the calicheamicin polyketide synthase leads to detection of a programmed octaketide and a proposal for enediyne biosynthesis.Crystal Structure of Thioesterase SgcE10 Supporting Common Polyene Intermediates in 9- and 10-Membered Enediyne Core Biosynthesis.Analysis of intact and dissected fungal polyketide synthase-nonribosomal peptide synthetase in vitro and in Saccharomyces cerevisiaeBiochemical determination of enzyme-bound metabolites: preferential accumulation of a programmed octaketide on the enediyne polyketide synthase CalE8Assembly line termination in cylindrocyclophane biosynthesis: discovery of an editing type II thioesterase domain in a type I polyketide synthase.A dual role for a polyketide synthase in dynemicin enediyne and anthraquinone biosynthesis.Characterization of an Anthracene Intermediate in Dynemicin Biosynthesis.
P2860
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P2860
Production of octaketide polyenes by the calicheamicin polyketide synthase CalE8: implications for the biosynthesis of enediyne core structures.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Production of octaketide polye ...... s of enediyne core structures.
@en
Production of octaketide polye ...... s of enediyne core structures.
@nl
type
label
Production of octaketide polye ...... s of enediyne core structures.
@en
Production of octaketide polye ...... s of enediyne core structures.
@nl
prefLabel
Production of octaketide polye ...... s of enediyne core structures.
@en
Production of octaketide polye ...... s of enediyne core structures.
@nl
P2093
P2860
P356
P1476
Production of octaketide polye ...... s of enediyne core structures.
@en
P2093
Craig A Townsend
Jason M Crawford
Katherine Belecki
P2860
P304
12564-12566
P356
10.1021/JA904391R
P407
P577
2009-09-01T00:00:00Z