FUS regulates genes coding for RNA-binding proteins in neurons by binding to their highly conserved introns.
about
The new (dis)order in RNA regulationDysregulated axonal RNA translation in amyotrophic lateral sclerosisFUS-mediated regulation of alternative RNA processing in neurons: insights from global transcriptome analysisAlterations in stress granule dynamics driven by TDP-43 and FUS: a link to pathological inclusions in ALS?Converging mechanisms in ALS and FTD: disrupted RNA and protein homeostasisRNA-binding proteins in neurodegeneration: Seq and you shall receiveA loss of FUS/TLS function leads to impaired cellular proliferationEarly lethality and neuronal proteinopathy in mice expressing cytoplasm-targeted FUS that lacks the RNA recognition motif.EWS and FUS bind a subset of transcribed genes encoding proteins enriched in RNA regulatory functionsCharacterization of genetic loss-of-function of Fus in zebrafish.Functions of FUS/TLS from DNA repair to stress response: implications for ALS.Building robust transcriptomes with master splicing factorsALS-associated FUS mutations result in compromised FUS alternative splicing and autoregulation.ALS-causative mutations in FUS/TLS confer gain and loss of function by altered association with SMN and U1-snRNP.Computational challenges, tools, and resources for analyzing co- and post-transcriptional events in high throughput.Improvements to the HITS-CLIP protocol eliminate widespread mispriming artifacts.Dissecting the expression relationships between RNA-binding proteins and their cognate targets in eukaryotic post-transcriptional regulatory networks.ALS mutations in TLS/FUS disrupt target gene expression.CLIPSeqTools--a novel bioinformatics CLIP-seq analysis suite.Minor intron splicing is regulated by FUS and affected by ALS-associated FUS mutantsScale Invariant Disordered Nanotopography Promotes Hippocampal Neuron Development and Maturation with Involvement of Mechanotransductive Pathways.FUsed in sarcoma is a novel regulator of manganese superoxide dismutase gene transcription.FUS-mediated alternative splicing in the nervous system: consequences for ALS and FTLD.Amyotrophic lateral sclerosis: an update on recent genetic insights.Brain pathology in myotonic dystrophy: when tauopathy meets spliceopathy and RNAopathy.RNA binding proteins: a common denominator of neuronal function and dysfunction.Invited review: decoding the pathophysiological mechanisms that underlie RNA dysregulation in neurodegenerative disorders: a review of the current state of the art.RNA mis-splicing in disease.FUS inclusions disrupt RNA localization by sequestering kinesin-1 and inhibiting microtubule detyrosination.Physiological functions and pathobiology of TDP-43 and FUS/TLS proteins.Position-specific binding of FUS to nascent RNA regulates mRNA length.Role of FET proteins in neurodegenerative disorders.RNA-binding proteins implicated in neurodegenerative diseases.Linking amyotrophic lateral sclerosis and spinal muscular atrophy through RNA-transcriptome homeostasis: a genomics perspective.Failure to Deliver and Translate-New Insights into RNA Dysregulation in ALS.FUS-regulated RNA metabolism and DNA damage repair: Implications for amyotrophic lateral sclerosis and frontotemporal dementia pathogenesis.A Regulatory Circuitry Between Gria2, miR-409, and miR-495 Is Affected by ALS FUS Mutation in ESC-Derived Motor Neurons.Distinct and Modular Organization of Protein Interacting Sites in Long Non-coding RNAs.Importance of Functional Loss of FUS in FTLD/ALS.A cytoplasmic long noncoding RNA LINC00470 as a new AKT activator to mediate glioblastoma cell autophagy.
P2860
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P2860
FUS regulates genes coding for RNA-binding proteins in neurons by binding to their highly conserved introns.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
FUS regulates genes coding for ...... heir highly conserved introns.
@en
FUS regulates genes coding for ...... heir highly conserved introns.
@nl
type
label
FUS regulates genes coding for ...... heir highly conserved introns.
@en
FUS regulates genes coding for ...... heir highly conserved introns.
@nl
prefLabel
FUS regulates genes coding for ...... heir highly conserved introns.
@en
FUS regulates genes coding for ...... heir highly conserved introns.
@nl
P2860
P50
P356
P1433
P1476
FUS regulates genes coding for ...... heir highly conserved introns.
@en
P2093
Alexandra Chang
Tadashi Nakaya
P2860
P304
P356
10.1261/RNA.037804.112
P407
P577
2013-02-06T00:00:00Z