The RING domain of TRAF2 plays an essential role in the inhibition of TNFalpha-induced cell death but not in the activation of NF-kappaB.
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Post-translational modifications as key regulators of TNF-induced necroptosisNF-κB, the first quarter-century: remarkable progress and outstanding questionsMolecular karyotypes of Hodgkin and Reed-Sternberg cells at disease onset reveal distinct copy number alterations in chemosensitive versus refractory Hodgkin lymphomaEmerging complexity of protein ubiquitination in the NF-κB pathway.TRAF2 phosphorylation promotes NF-κB-dependent gene expression and inhibits oxidative stress-induced cell death.In TNF-stimulated cells, RIPK1 promotes cell survival by stabilizing TRAF2 and cIAP1, which limits induction of non-canonical NF-kappaB and activation of caspase-8Tumor necrosis factor (TNF) receptor-associated factor (TRAF)-interacting protein (TRIP) negatively regulates the TRAF2 ubiquitin-dependent pathway by suppressing the TRAF2-sphingosine 1-phosphate (S1P) interaction.SHARPIN is a key regulator of immune and inflammatory responsesRole of WWOX and NF-κB in lung cancer progressionTRAF2 regulates TNF and NF-κB signalling to suppress apoptosis and skin inflammation independently of Sphingosine kinase 1TRAF2 exerts opposing effects on basal and TNFα-induced activation of the classic IKK complex in hematopoietic cells in miceTRAF molecules in cell signaling and in human diseasesTNFR1 signaling kinetics: spatiotemporal control of three phases of IKK activation by posttranslational modification.T-cell intrinsic effects of GITR and 4-1BB during viral infection and cancer immunotherapy.NFκB and ubiquitination: partners in disarming RIPK1-mediated cell death.Regulation of NF-κB by TNF family cytokines.Two coordinated mechanisms underlie tumor necrosis factor alpha-induced immediate and delayed IκB kinase activation.A protective strategy against hyperinflammatory responses requiring the nontranscriptional actions of GPS2.A novel dual signaling axis for NSP 5a3a induced apoptosis in head and neck carcinoma.In mouse embryonic fibroblasts, neither caspase-8 nor cellular FLICE-inhibitory protein (FLIP) is necessary for TNF to activate NF-κB, but caspase-8 is required for TNF to cause cell death, and induction of FLIP by NF-κB is required to prevent it.USP4 targets TAK1 to downregulate TNFα-induced NF-κB activation.TRADD, TRAF2, RIP1 and TAK1 are required for TNF-α-induced pro-labour mediators in human primary myometrial cells.Cardioprotective Role of Tumor Necrosis Factor Receptor-Associated Factor 2 by Suppressing Apoptosis and Necroptosis.
P2860
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P2860
The RING domain of TRAF2 plays an essential role in the inhibition of TNFalpha-induced cell death but not in the activation of NF-kappaB.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
The RING domain of TRAF2 plays ...... n the activation of NF-kappaB.
@en
The RING domain of TRAF2 plays ...... n the activation of NF-kappaB.
@nl
type
label
The RING domain of TRAF2 plays ...... n the activation of NF-kappaB.
@en
The RING domain of TRAF2 plays ...... n the activation of NF-kappaB.
@nl
prefLabel
The RING domain of TRAF2 plays ...... n the activation of NF-kappaB.
@en
The RING domain of TRAF2 plays ...... n the activation of NF-kappaB.
@nl
P2093
P2860
P1476
The RING domain of TRAF2 plays ...... n the activation of NF-kappaB.
@en
P2093
Hasem Habelhah
Ken Blackwell
Laiqun Zhang
Zhaohui Shi
P2860
P304
P356
10.1016/J.JMB.2010.01.008
P407
P577
2010-01-11T00:00:00Z