The X-ray structure of RANTES: heparin-derived disaccharides allows the rational design of chemokine inhibitors.
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Structural basis of chemokine sequestration by CrmD, a poxvirus-encoded tumor necrosis factor receptorEngineering of Lactobacillus jensenii to secrete RANTES and a CCR5 antagonist analogue as live HIV-1 blockersStructural and Functional Basis of CXCL12 (Stromal Cell-derived Factor-1 ) Binding to HeparinHeparin-induced cis- and trans-Dimerization Modes of the Thrombospondin-1 N-terminal DomainDual GPCR and GAG mimicry by the M3 chemokine decoy receptorStructure of mouse IP-10, a chemokineStructural and functional studies of the potent anti-HIV chemokine variant P2-RANTESOligomeric Structure of the Chemokine CCL5/RANTES from NMR, MS, and SAXS DataA Model of GAG/MIP-2/CXCR2 Interfaces and Its Functional EffectsEvidence for a granule targeting sequence within platelet factor 4.Finding a needle in a haystack: development of a combinatorial virtual screening approach for identifying high specificity heparin/heparan sulfate sequence(s).Structural Evidence for the Tetrameric Assembly of Chemokine CCL11 and the Glycosaminoglycan Arixtra™Synthetic di-sulfated iduronic acid attenuates asthmatic response by blocking T-cell recruitment to inflammatory sitesThe antimicrobial activity of CCL28 is dependent on C-terminal positively-charged amino acids.The "CPC clip motif": a conserved structural signature for heparin-binding proteins.Structural Analysis of Chemokine Receptor-Ligand Interactions.Structural NMR of protein oligomers using hybrid methods.Molecular engineering of RANTES peptide mimetics with potent anti-HIV-1 activity.Solution structure of the complex between poxvirus-encoded CC chemokine inhibitor vCCI and human MIP-1beta.Characterisation of the interaction of neuropilin-1 with heparin and a heparan sulfate mimetic library of heparin-derived sugars.Chemokine and chemokine receptor structure and interactions: implications for therapeutic strategies.Interactions of the Chemokine CCL5/RANTES with Medium-Sized Chondroitin Sulfate LigandsMechanisms regulating the secretion of the promalignancy chemokine CCL5 by breast tumor cells: CCL5's 40s loop and intracellular glycosaminoglycansUnphosphorylated STAT3 accumulates in response to IL-6 and activates transcription by binding to NFkappaBThe Interaction of Heparin Tetrasaccharides with Chemokine CCL5 Is Modulated by Sulfation Pattern and pHGlycosaminoglycan analogs as a novel anti-inflammatory strategyNMR in the Analysis of Functional Chemokine Interactions and Drug DiscoveryCXCL1/MGSA Is a Novel Glycosaminoglycan (GAG)-binding Chemokine: STRUCTURAL EVIDENCE FOR TWO DISTINCT NON-OVERLAPPING BINDING DOMAINSExamination of Glycosaminoglycan Binding Sites on the XCL1 DimerRational design of novel HIV-1 entry inhibitors by RANTES engineeringMolecular basis of glycosaminoglycan heparin binding to the chemokine CXCL1 dimer.Structural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3A beginner's guide to chemokines.Targeting CCL5 in inflammation.The "in and out" of glucosamine 6-O-sulfation: the 6th sense of heparan sulfate.Characterization of the interactions of vMIP-II, and a dimeric variant of vMIP-II, with glycosaminoglycans.Chemokines and GlycosaminoglycansThe sweet spot: how GAGs help chemokines guide migrating cells.Tunable heparan sulfate mimetics for modulating chemokine activityComputational analysis of interactions in structurally available protein-glycosaminoglycan complexes.
P2860
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P2860
The X-ray structure of RANTES: heparin-derived disaccharides allows the rational design of chemokine inhibitors.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
The X-ray structure of RANTES: ...... esign of chemokine inhibitors.
@en
The X-ray structure of RANTES: ...... esign of chemokine inhibitors.
@nl
type
label
The X-ray structure of RANTES: ...... esign of chemokine inhibitors.
@en
The X-ray structure of RANTES: ...... esign of chemokine inhibitors.
@nl
prefLabel
The X-ray structure of RANTES: ...... esign of chemokine inhibitors.
@en
The X-ray structure of RANTES: ...... esign of chemokine inhibitors.
@nl
P2093
P50
P921
P1433
P1476
The X-ray structure of RANTES: ...... design of chemokine inhibitors
@en
P2093
Amanda E I Proudfoot
Andreas Kungl
Axel Harrenga
Frédéric Borlat
Jeffrey P Shaw
Karen Roulin
P304
P356
10.1016/J.STR.2004.08.014
P577
2004-11-01T00:00:00Z