Optimized Nile Red efflux assay of AcrAB-TolC multidrug efflux system shows competition between substrates
about
RND-type drug efflux pumps from Gram-negative bacteria: molecular mechanism and inhibitionDirected evolution of an E. coli inner membrane transporter for improved efflux of biofuel moleculesMultidrug binding properties of the AcrB efflux pump characterized by molecular dynamics simulations.Microbial efflux systems and inhibitors: approaches to drug discovery and the challenge of clinical implementationCorrelation between AcrB trimer association affinity and efflux activityDetermination of real-time efflux phenotypes in Escherichia coli AcrB binding pocket phenylalanine mutants using a 1,2'-dinaphthylamine efflux assay.False extended-spectrum {beta}-lactamase phenotype in clinical isolates of Escherichia coli associated with increased expression of OXA-1 or TEM-1 penicillinases and loss of porins.Fluorescence-based assessment of plasma-induced hydrophilicity in microfluidic devices via Nile Red adsorption and depletion.Electrical spiking in Escherichia coli probed with a fluorescent voltage-indicating protein.Molecular mechanism of MBX2319 inhibition of Escherichia coli AcrB multidrug efflux pump and comparison with other inhibitorsFluorescence correlation spectroscopy measurements of the membrane protein TetA in Escherichia coli suggest rapid diffusion at short length scales.Repressive mutations restore function-loss caused by the disruption of trimerization in Escherichia coli multidrug transporter AcrB.Characterization of a novel pyranopyridine inhibitor of the AcrAB efflux pump of Escherichia coliAn unusual class of anthracyclines potentiate Gram-positive antibiotics in intrinsically resistant Gram-negative bacteria.Structure-activity relationships of a novel pyranopyridine series of Gram-negative bacterial efflux pump inhibitors.The challenge of efflux-mediated antibiotic resistance in Gram-negative bacteria.Three Dimensional Checkerboard Synergy Analysis of Colistin, Meropenem, Tigecycline against Multidrug-Resistant Clinical Klebsiella pneumonia IsolatesInteraction of antibacterial compounds with RND efflux pumps in Pseudomonas aeruginosaImportance of Real-Time Assays To Distinguish Multidrug Efflux Pump-Inhibiting and Outer Membrane-Destabilizing Activities in Escherichia coli.Design of New Antibacterial Enhancers Based on AcrB's Structure and the Evaluation of Their Antibacterial Enhancement Activity.Membrane transport systems and the biodegradation potential and pathogenicity of genus Rhodococcus.A Simple Method for Assessment of MDR Bacteria for Over-Expressed Efflux Pumps.How to Measure Export via Bacterial Multidrug Resistance Efflux PumpsNew Roads Leading to Old Destinations: Efflux Pumps as Targets to Reverse Multidrug Resistance in Bacteria.Pimozide Inhibits the AcrAB-TolC Efflux Pump in Escherichia coli.Novel Piperazine Arylideneimidazolones Inhibit the AcrAB-TolC Pump in Escherichia coli and Simultaneously Act as Fluorescent Membrane Probes in a Combined Real-Time Influx and Efflux Assay.Evidence of a Substrate-Discriminating Entrance Channel in the Lower Porter Domain of the Multidrug Resistance Efflux Pump AcrBSubstrate path in the AcrB multidrug efflux pump of Escherichia coli.A fluorescent microplate assay quantifies bacterial efflux and demonstrates two distinct compound binding sites in AcrB.Phytochemicals increase the antibacterial activity of antibiotics by acting on a drug efflux pump.High-Throughput Flow Cytometry Screening of Multidrug Efflux Systems.Efflux inhibition by selective serotonin reuptake inhibitors in Escherichia coli.Controlling the Resting Membrane Potential of Cells with Conducting Polymer Microwires.Multiparametric Profiling for Identification of Chemosensitizers against Gram-Negative Bacteria.Nitrothiophene carboxamides, a novel narrow spectrum antibacterial series: Mechanism of action and Efficacy.A cell-based infection assay identifies efflux pump modulators that reduce bacterial intracellular load.
P2860
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P2860
Optimized Nile Red efflux assay of AcrAB-TolC multidrug efflux system shows competition between substrates
description
2010 nî lūn-bûn
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2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
@zh-my
2010年学术文章
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2010年學術文章
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name
Optimized Nile Red efflux assa ...... competition between substrates
@en
Optimized Nile Red efflux assa ...... competition between substrates
@nl
type
label
Optimized Nile Red efflux assa ...... competition between substrates
@en
Optimized Nile Red efflux assa ...... competition between substrates
@nl
prefLabel
Optimized Nile Red efflux assa ...... competition between substrates
@en
Optimized Nile Red efflux assa ...... competition between substrates
@nl
P2093
P2860
P356
P1476
Optimized Nile Red efflux assa ...... competition between substrates
@en
P2093
Brian Karamian
Hiroshi Nikaido
Jürgen A Bohnert
P2860
P304
P356
10.1128/AAC.00620-10
P407
P577
2010-07-06T00:00:00Z