Evidence that the conformation of unliganded human plasminogen is maintained via an intramolecular interaction between the lysine-binding site of kringle 5 and the N-terminal peptide.
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Crystal structure of the native plasminogen reveals an activation-resistant compact conformationReduction of canine plasminogen leads to an expanded molecule which precipitates.Effects on human plasminogen conformation and activation rate caused by interaction with VEK-30, a peptide derived from the group A streptococcal M-like protein (PAM).Fibrinolytic cross-talk: a new mechanism for plasmin formation.Skizzle is a novel plasminogen- and plasmin-binding protein from Streptococcus agalactiae that targets proteins of human fibrinolysis to promote plasmin generationRapid binding of plasminogen to streptokinase in a catalytic complex reveals a three-step mechanism.Structural basis of hepatocyte growth factor/scatter factor and MET signalling.Decoy plasminogen receptor containing a selective Kunitz-inhibitory domain.The interaction of streptococcal enolase with canine plasminogen: the role of surfaces in complex formation.Monoclonal antibodies detect receptor-induced binding sites in Glu-plasminogen.Lipoprotein (a): truly a direct prothrombotic factor in cardiovascular disease?Small-molecule modulators of zymogen activation in the fibrinolytic and coagulation systems.Natural and engineered plasmin inhibitors: applications and design strategies.Peptides with 6-Aminohexanoic Acid: Synthesis and Evaluation as Plasmin Inhibitors.Elevated lipoprotein (a) levels are an independent risk factor for retinal vein occlusion.Nonlysine-analog plasminogen modulators promote autoproteolytic generation of plasmin(ogen) fragments with angiostatin-like activity.A ligand-induced conformational change in apolipoprotein(a) enhances covalent Lp(a) formation.SMTP (Stachybotrys microspora triprenyl phenol) enhances clot clearance in a pulmonary embolism model in rats.Rapid-reaction kinetic characterization of the pathway of streptokinase-plasmin catalytic complex formation.Canine plasminogen: spectral responses to changes in 6-aminohexanoate and temperature.Structure-activity relationships of 11 new congeners of the SMTP plasminogen modulator.Functional hierarchy of plasminogen kringles 1 and 4 in fibrinolysis and plasmin-induced cell detachment and apoptosis.Stachybotrydial selectively enhances fibrin binding and activation of Glu-plasminogen.Expression and characterization of recombinant human micro-plasminogen.The effects of hydrostatic pressure on the conformation of plasminogen.Plasminogen Structural Domains Exhibit Different Functions When Associated with Cell Surface GRP78 or the Voltage-dependent Anion Channel
P2860
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P2860
Evidence that the conformation of unliganded human plasminogen is maintained via an intramolecular interaction between the lysine-binding site of kringle 5 and the N-terminal peptide.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Evidence that the conformation ...... 5 and the N-terminal peptide.
@en
Evidence that the conformation ...... 5 and the N-terminal peptide.
@nl
type
label
Evidence that the conformation ...... 5 and the N-terminal peptide.
@en
Evidence that the conformation ...... 5 and the N-terminal peptide.
@nl
prefLabel
Evidence that the conformation ...... 5 and the N-terminal peptide.
@en
Evidence that the conformation ...... 5 and the N-terminal peptide.
@nl
P2093
P2860
P356
P1433
P1476
Evidence that the conformation ...... 5 and the N-terminal peptide.
@en
P2093
C S Cockell
J M Marshall
K M Dawson
S A Cederholm-Williams
P2860
P304
P356
10.1042/BJ3330099
P407
P478
333 ( Pt 1)
P577
1998-07-01T00:00:00Z