Lysosomal positioning coordinates cellular nutrient responses. - Wikidata - wikimedia - TriplyDB

Lysosomal positioning coordinates cellular nutrient responses.

Lysosomal positioning coordinates cellular nutrient responses.

http://www.wikidata.org/entity/Q42160015

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Dysregulation of the autophagy-endolysosomal system in amyotrophic lateral sclerosis and related motor neuron diseases Nutrient deprivation induces α-synuclein aggregation through endoplasmic reticulum stress response and SREBP2 pathway Dysregulation of lysosomal morphology by pathogenic LRRK2 is corrected by TPC2 inhibition mTOR regulates lysosomal ATP-sensitive two-pore Na(+) channels to adapt to metabolic state SVIP induces localization of p97/VCP to the plasma and lysosomal membranes and regulates autophagy Clarifying lysosomal storage diseases Amino acids and mTORC1: from lysosomes to disease βA3/A1-crystallin: more than a lens protein The lysosome: from waste bag to potential therapeutic target Lysosomal proteins in cell death and autophagy Time course decomposition of cell heterogeneity in TFEB signaling states reveals homeostatic mechanisms restricting the magnitude and duration of TFEB responses to mTOR activity modulation.Cholesterol and ORP1L-mediated ER contact sites control autophagosome transport and fusion with the endocytic pathway.BORC, a multisubunit complex that regulates lysosome positioning.Optogenetic control of molecular motors and organelle distributions in cells.Macrophage Receptor with Collagenous Structure (MARCO) Is Processed by either Macropinocytosis or Endocytosis-Autophagy Pathway Arf-like GTPase Arl8: Moving from the periphery to the center of lysosomal biology A lysosome-centered view of nutrient homeostasis Reduced cathepsins B and D cause impaired autophagic degradation that can be almost completely restored by overexpression of these two proteases in Sap C-deficient fibroblasts TANGO1 and Mia2/cTAGE5 (TALI) cooperate to export bulky pre-chylomicrons/VLDLs from the endoplasmic reticulum Where is mTOR and what is it doing there?Spatial control of the TSC complex integrates insulin and nutrient regulation of mTORC1 at the lysosome Stimulation of autophagy improves endoplasmic reticulum stress-induced diabetes Anti-remodeling effects of rapamycin in experimental heart failure: dose response and interaction with angiotensin receptor blockade A Novel High Content Imaging-Based Screen Identifies the Anti-Helminthic Niclosamide as an Inhibitor of Lysosome Anterograde Trafficking and Prostate Cancer Cell Invasion Microtubules that form the stationary lattice of muscle fibers are dynamic and nucleated at Golgi elements.TBK-1 Promotes Autophagy-Mediated Antimicrobial Defense by Controlling Autophagosome Maturation Rab family proteins regulate the endosomal trafficking and function of RGS4.Proteasome failure promotes positioning of lysosomes around the aggresome via local block of microtubule-dependent transport.PKA-dependent dynein switching from lysosomes to adenovirus: a novel form of host-virus competition.Agent-based modeling of autophagy reveals emergent regulatory behavior of spatio-temporal autophagy dynamics.Optogenetic control of organelle transport and positioning SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair.Autophagy activation reduces renal tubular injury induced by urinary proteins.Epigenetic control of autophagy by microRNAs in ovarian cancer Ras regulates kinesin 13 family members to control cell migration pathways in transformed human bronchial epithelial cells.Two-Pore Channels and Parkinson's Disease: Where's the Link?Rab7 GTPase controls lipid metabolic signaling in myeloid-derived suppressor cells.Microtubules and their role in cellular stress in cancer Activity-independent targeting of mTOR to lysosomes in primary osteoclasts Atg17/FIP200 localizes to perilysosomal Ref(2)P aggregates and promotes autophagy by activation of Atg1 in Drosophila.

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Lysosomal positioning coordinates cellular nutrient responses.

http://www.wikidata.org/entity/Q42160015

description

2011 nî lūn-bûn

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

@zh-tw

2011年论文

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2011年论文

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2011年论文

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name

Lysosomal positioning coordinates cellular nutrient responses.

@en

Lysosomal positioning coordinates cellular nutrient responses.

@nl

type

label

Lysosomal positioning coordinates cellular nutrient responses.

@en

Lysosomal positioning coordinates cellular nutrient responses.

@nl

prefLabel

Lysosomal positioning coordinates cellular nutrient responses.

@en

Lysosomal positioning coordinates cellular nutrient responses.

@nl

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Nature Cell Biology

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Lysosomal positioning coordinates cellular nutrient responses

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P2093

David C Rubinsztein

http://www.w3.org/2001/XMLSchema#string

Esteban A Roberts

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Farah H Siddiqi

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Fiona M Menzies

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Luca Jahreiss

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Maike Lichtenberg

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Marie Futter

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Sara Imarisio

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Shinji Saiki

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P2860

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

Novel small GTPase subfamily capable of associating with tubulin is required for chromosome segregation

Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids

The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

Activity of TSC2 is inhibited by AKT-mediated phosphorylation and membrane partitioning

Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb

A novel kinesin-like protein, KIF1Bbeta3 is involved in the movement of lysosomes to the cell periphery in non-neuronal cells

Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages

The role of autophagy during the early neonatal starvation period

Autophagy: from phenomenology to molecular understanding in less than a decade

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453-460

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10.1038/NCB2204

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4

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13

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Viktor Korolchuk

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2011-03-13T00:00:00Z

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50364443

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21394080

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3071334

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