Lysosomal cysteine endopeptidases mediate interleukin 1-stimulated cartilage proteoglycan degradation

Lysosomal cysteine endopeptidases mediate interleukin 1-stimulated cartilage proteoglycan degradation

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http://www.wikidata.org/entity/Q42161442
Cathepsin B in osteoarthritis: cytochemical and histochemical analysis of human femoral head cartilage.In vivo model of cartilage degradation--effects of a matrix metalloproteinase inhibitor.Temporal pattern of cysteine endopeptidase (cathepsin B) expression in cartilage and synovium from rabbit knees with experimental osteoarthritis: gene expression in chondrocytes in response to interleukin-1 and matrix depletion.Inhibition of bone resorption by selective inactivators of cysteine proteinases.Proteolytic mechanisms of cartilage breakdown: a target for arthritis therapy?Inhibitors of collagenase but not of gelatinase reduce cartilage explant proteoglycan breakdown despite only low levels of matrix metalloproteinase activity.A retinoblastoma susceptibility gene product, RB, targeting protease is regulated through the cell cycle.Expression of functional recombinant human procathepsin B in mammalian cells.Activation of procollagenases is a key control point in cartilage collagen degradation: interaction of serine and metalloproteinase pathways.The active-site residue Cys-29 is responsible for the neutral-pH inactivation and the refolding barrier of human cathepsin B.
P2860

Lysosomal cysteine endopeptidases mediate interleukin 1-stimulated cartilage proteoglycan degradation

Item
http://www.wikidata.org/entity/Q42161442
description
1992 nî lūn-bûn
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1992年の論文
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1992年論文
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1992年論文
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1992年論文
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@zh-mo
1992年論文
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1992年论文
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1992年论文
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name
Lysosomal cysteine endopeptida ...... ilage proteoglycan degradation
@en
Lysosomal cysteine endopeptida ...... ilage proteoglycan degradation
@nl
type
label
Lysosomal cysteine endopeptida ...... ilage proteoglycan degradation
@en
Lysosomal cysteine endopeptida ...... ilage proteoglycan degradation
@nl
prefLabel
Lysosomal cysteine endopeptida ...... ilage proteoglycan degradation
@en
Lysosomal cysteine endopeptida ...... ilage proteoglycan degradation
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P478
P577
P5875
P698
P921
P932
P356
P1433
P1476
Lysosomal cysteine endopeptida ...... ilage proteoglycan degradation
@en
P2093
P2860
P304
P31
P356
P407
P478
P577
P5875
P698
P921
P932