Requirement for class II phosphoinositide 3-kinase C2alpha in maintenance of glomerular structure and function
about
PodocytesPodocyte endocytosis in the regulation of the glomerular filtration barrierThe function of endocytosis in podocytesSignaling by the phosphoinositide 3-kinase family in immune cellsRole of dynamin, synaptojanin, and endophilin in podocyte foot processes.Glomerular proteinuria: a complex interplay between unique players.Large-scale RNA interference screening in mammalian cells identifies novel regulators of mutant huntingtin aggregation.PI3K in cancer: divergent roles of isoforms, modes of activation and therapeutic targeting.Investigating mechanisms of chronic kidney disease in mouse modelsClass III PI 3-kinase is the main source of PtdIns3P substrate and membrane recruitment signal for PIKfyve constitutive function in podocyte endomembrane homeostasisSpinster 2, a sphingosine-1-phosphate transporter, plays a critical role in inflammatory and autoimmune diseases.Inactivation of the Class II PI3K-C2β Potentiates Insulin Signaling and SensitivityInactivation of class II PI3K-C2α induces leptin resistance, age-dependent insulin resistance and obesity in male mice.Signaling from the podocyte intercellular junction to the actin cytoskeleton.Transient receptor potential vanilloid 1 (TRPV1), TRPV4, and the kidney.New insight into the intracellular roles of class II phosphoinositide 3-kinases.Class II phosphoinositide 3-kinase C2alpha: what we learned so farPodocyte-actin dynamics in health and disease.Phosphoinositide 3-Kinase-C2α Regulates Polycystin-2 Ciliary Entry and Protects against Kidney Cyst Formation.Vps34 deficiency reveals the importance of endocytosis for podocyte homeostasis.Conditional knockout of pik3c3 causes a murine muscular dystrophy.Dentin Dysplasia in Notum Knockout Mice.Combined deficiency of PI3KC2α and PI3KC2β reveals a nonredundant role for PI3KC2α in regulating mouse platelet structure and thrombus stability.The class II PI 3-kinase, PI3KC2α, links platelet internal membrane structure to shear-dependent adhesive function.Endothelial PI3K-C2α, a class II PI3K, has an essential role in angiogenesis and vascular barrier function.
P2860
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P2860
Requirement for class II phosphoinositide 3-kinase C2alpha in maintenance of glomerular structure and function
description
2010 nî lūn-bûn
@nan
2010年の論文
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2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
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2010年论文
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name
Requirement for class II phosp ...... merular structure and function
@en
Requirement for class II phosp ...... merular structure and function
@nl
type
label
Requirement for class II phosp ...... merular structure and function
@en
Requirement for class II phosp ...... merular structure and function
@nl
prefLabel
Requirement for class II phosp ...... merular structure and function
@en
Requirement for class II phosp ...... merular structure and function
@nl
P2093
P2860
P356
P1476
Requirement for class II phosp ...... merular structure and function
@en
P2093
Christopher M DaCosta
David P Harris
David R Powell
Gwenn M Hansen
Juliane Humphries
Kanchan G Jhaver
Karen Moberg
Marie Wims
Melanie K Shadoan
P2860
P356
10.1128/MCB.00468-10
P407
P577
2010-10-25T00:00:00Z