Genetic rescue of Leishmania deficiency in porphyrin biosynthesis creates mutants suitable for analysis of cellular events in uroporphyria and for photodynamic therapy.
about
Molecular determinants and regulation of Leishmania virulence.New "light" for one-world approach toward safe and effective control of animal diseases and insect vectors from leishmaniac perspectivesHeme mediates cytotoxicity from artemisinin and serves as a general anti-proliferation targetIntracellular targeting specificity of novel phthalocyanines assessed in a host-parasite model for developing potential photodynamic medicineCellular growth and mitochondrial ultrastructure of leishmania (Viannia) braziliensis promastigotes are affected by the iron chelator 2,2-dipyridylGenome-wide analysis reveals novel genes essential for heme homeostasis in Caenorhabditis elegansLack of heme synthesis in a free-living eukaryote.Identification and phylogenetic analysis of heme synthesis genes in trypanosomatids and their bacterial endosymbionts.Heme-induced ROS in Trypanosoma cruzi activates CaMKII-like that triggers epimastigote proliferation. One helpful effect of ROSDevelopment of Vaccines against Visceral LeishmaniasisIn vitro and in vivo studies of the utility of dimethyl and diethyl carbaporphyrin ketals in treatment of cutaneous leishmaniasis.Functional Characterization of Monomeric GTPase Rab1 in the Secretory Pathway of LeishmaniaLeishmania requires Rab7-mediated degradation of endocytosed hemoglobin for their growth.Intracellular trafficking of porphyrins.Transgenic Leishmania model for delta-aminolevulinate-inducible monospecific uroporphyria: cytolytic phototoxicity initiated by singlet oxygen-mediated inactivation of proteins and its ablation by endosomal mobilization of cytosolic uroporphyrin.Rab5-mediated endosome-endosome fusion regulates hemoglobin endocytosis in Leishmania donovani.Role of heme and heme-proteins in trypanosomatid essential metabolic pathways.Leishmania spp.: delta-aminolevulinate-inducible neogenesis of porphyria by genetic complementation of incomplete heme biosynthesis pathway.Combinational sensitization of Leishmania with uroporphyrin and aluminum phthalocyanine synergistically enhances their photodynamic inactivation in vitro and in vivo.Aminophthalocyanine-Mediated Photodynamic Inactivation of Leishmania tropica.Photodynamic sensitization of Leishmania amazonensis in both extracellular and intracellular stages with aluminum phthalocyanine chloride for photolysis in vitroLeishmania (Viannia) panamensis: an in vitro assay using the expression of GFP for screening of antileishmanial drug.Identification of specific inhibitors for a trypanosomatid RNA editing reaction.Photodynamic vaccination of hamsters with inducible suicidal mutants of Leishmania amazonensis elicits immunity against visceral leishmaniasis.Delta-aminolevulinate-induced host-parasite porphyric disparity for selective photolysis of transgenic Leishmania in the phagolysosomes of mononuclear phagocytes: a potential novel platform for vaccine delivery.Vaccination with leishmania hemoglobin receptor-encoding DNA protects against visceral leishmaniasis.Leishmania major possesses a unique HemG-type protoporphyrinogen IX oxidase.Hemoglobin receptor in Leishmania is a hexokinase located in the flagellar pocket.Photodynamic Vaccination of BALB/c Mice for Prophylaxis of Cutaneous Leishmaniasis Caused by Leishmania amazonensis.
P2860
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P2860
Genetic rescue of Leishmania deficiency in porphyrin biosynthesis creates mutants suitable for analysis of cellular events in uroporphyria and for photodynamic therapy.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Genetic rescue of Leishmania d ...... and for photodynamic therapy.
@en
Genetic rescue of Leishmania d ...... and for photodynamic therapy.
@nl
type
label
Genetic rescue of Leishmania d ...... and for photodynamic therapy.
@en
Genetic rescue of Leishmania d ...... and for photodynamic therapy.
@nl
prefLabel
Genetic rescue of Leishmania d ...... and for photodynamic therapy.
@en
Genetic rescue of Leishmania d ...... and for photodynamic therapy.
@nl
P2093
P2860
P356
P1476
Genetic rescue of Leishmania d ...... and for photodynamic therapy.
@en
P2093
Bala Krishna Kolli
Daniel A Peterson
Hiroya Ito
Jerome Franklin Sah
Shigeru Sassa
P2860
P304
14902-14909
P356
10.1074/JBC.M200107200
P407
P577
2002-02-08T00:00:00Z