Human apurinic/apyrimidinic endonuclease (Ape1) and its N-terminal truncated form (AN34) are involved in DNA fragmentation during apoptosis.
about
APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process.Repair of oxidative DNA damage and cancer: recent progress in DNA base excision repairEmerging roles of the nucleolus in regulating the DNA damage response: the noncanonical DNA repair enzyme APE1/Ref-1 as a paradigmatical exampleCross-talk-free dual-color fluorescence cross-correlation spectroscopy for the study of enzyme activity.The many functions of APE1/Ref-1: not only a DNA repair enzymePolymer-based dense fluidic networks for high throughput screening with ultrasensitive fluorescence detection.Gene expression profile of esophageal cancer in North East India by cDNA microarray analysis.Characterization of splice variants of human caspase-activated DNase with CIDE-N structure and function.Identification and characterization of human apurinic/apyrimidinic endonuclease-1 inhibitorsDominant mutation of the TREX1 exonuclease gene in lupus and Aicardi-Goutieres syndrome.Gene-targeted mice lacking the Trex1 (DNase III) 3'-->5' DNA exonuclease develop inflammatory myocarditis.Endonuclease activation and chromosomal DNA fragmentation during apoptosis in leukemia cells.Characterization of the 3' --> 5' exonuclease activity found in human nucleoside diphosphate kinase 1 (NDK1) and several of its homologues.Regulation of limited N-terminal proteolysis of APE1 in tumor via acetylation and its role in cell proliferation.Prediction of survival prognosis of non-small cell lung cancer by APE1 through regulation of Epithelial-Mesenchymal Transition.Functional regulation of the apurinic/apyrimidinic endonuclease 1 by nucleophosmin: impact on tumor biology.Modulation of DNA fragmentation factor 40 nuclease activity by poly(ADP-ribose) polymerase-1.Altered intracellular redox status in Gaucher disease fibroblasts and impairment of adaptive response against oxidative stress.Crystallization and preliminary X-ray analysis of human endonuclease 1 (APE1) in complex with an oligonucleotide containing a 5,6-dihydrouracil (DHU) or an alpha-anomeric 2'-deoxyadenosine (alphadA) modified base.Role of the unstructured N-terminal domain of the hAPE1 (human apurinic/apyrimidinic endonuclease 1) in the modulation of its interaction with nucleic acids and NPM1 (nucleophosmin).DNA repair protein APE1 is involved in host response during pneumococcal meningitis and its expression can be modulated by vitamin B6.The extracellular role of DNA damage repair protein APE1 in regulation of IL-6 expression.
P2860
Q24329154-00C06589-72FB-4308-AFC4-7DF9980FBCF2Q26822957-877BED4E-7330-439D-992B-04C33F7AA937Q27026649-677FB2F8-EE34-407E-A164-CF73840E5E9CQ33523855-CE4D416E-D66A-4547-A83A-435205851933Q33609187-29AFE4B5-31C5-4CAC-AB4A-7F25AFB6D30DQ33703877-2263F1CD-D875-4A50-BA5E-0F45014CC406Q34099305-F3636FB9-0709-4600-BA5D-C797BD74CB05Q34321342-3BD0E18C-56EE-47D0-9492-C4B4C13867E7Q34334481-1D0E28BA-2FA4-4492-8318-E423B02C32C7Q35213485-DD36CC8A-98C2-472D-BE3B-700FBA40B515Q35663520-6BC66DB3-4C7F-40F0-8835-CCF90BB3D9ACQ36546910-14B028B2-F7D1-421B-859B-126122189B4EQ36916569-0B932A84-839A-4F0B-BBEC-70F1A9C5A107Q37225608-60F2B9AC-1691-4133-8682-CB4F4210B356Q37317599-BF7E5406-0FE2-4888-B3E7-F736E610184BQ39129437-4C869F44-6CAC-47D6-A5CC-7C42572E62E8Q40460134-CA378DB8-F0BA-4127-8C7B-E002EB9F5DBEQ42617617-5A75C48B-7903-439E-9D6C-D1BB263873C4Q42737383-7EAEBC57-4702-4C15-ABBB-D3CF9DFACC52Q44740203-2A122CFC-6DB4-4D03-98F4-F36BD4CF57BFQ46242792-28565C88-5495-4709-A819-C7F99288B90CQ48019408-7DF4F39D-B93D-4BDF-8DD9-06ECFC0EC455
P2860
Human apurinic/apyrimidinic endonuclease (Ape1) and its N-terminal truncated form (AN34) are involved in DNA fragmentation during apoptosis.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Human apurinic/apyrimidinic en ...... ragmentation during apoptosis.
@en
Human apurinic/apyrimidinic endonuclease
@nl
type
label
Human apurinic/apyrimidinic en ...... ragmentation during apoptosis.
@en
Human apurinic/apyrimidinic endonuclease
@nl
prefLabel
Human apurinic/apyrimidinic en ...... ragmentation during apoptosis.
@en
Human apurinic/apyrimidinic endonuclease
@nl
P2093
P2860
P356
P1476
Human apurinic/apyrimidinic en ...... ragmentation during apoptosis.
@en
P2093
Akira Yoshida
Ann-Charlotte Bergman
Dominic G Rothwell
Ettore Appella
Ian D Hickson
John N Weinstein
Manabu Inuzuka
Mark Waltham
Philippe Pourquier
Takanori Ueda
P2860
P304
37768-37776
P356
10.1074/JBC.M304914200
P407
P50
P577
2003-07-03T00:00:00Z