about
Synthesis and characterization of HE-24.8: a polymeric contrast agent for magnetic resonance angiography.Human erythrocytes bind and inactivate type 5 adenovirus by presenting Coxsackie virus-adenovirus receptor and complement receptor 1.In Vivo Nanotoxicity Testing using the Zebrafish Embryo Assay.E-selectin is a viable route of infection for polymer-coated adenovirus retargeting in TNF-α-activated human umbilical vein endothelial cells.Coating of adenovirus type 5 with polymers containing quaternary amines prevents binding to blood components.Doxorubicin release is not a prerequisite for the in vitro cytotoxicity of HPMA-based pharmaceuticals: in vitro effect of extra drug-free GlyPheLeuGly sequences.Virotherapy of ovarian cancer with polymer-cloaked adenovirus retargeted to the epidermal growth factor receptor.HPMA copolymers containing doxorubicin bound by a proteolytically or hydrolytically cleavable bond: comparison of biological properties in vitro.Effect of intratumoral injection on the biodistribution and the therapeutic potential of HPMA copolymer-based drug delivery systems.Image-guided and passively tumour-targeted polymeric nanomedicines for radiochemotherapy.HPMA-based polymer therapeutics improve the efficacy of surgery, of radiotherapy and of chemotherapy combinations.N-(2-Hydroxypropyl)methacrylamide-based polymer conjugates with pH-controlled activation of doxorubicin for cell-specific or passive tumour targeting. Synthesis by RAFT polymerisation and physicochemical characterisation.Chemical conjugation of cowpea mosaic viruses with reactive HPMA-based polymers.Intracerebral implantation of hydrogel-coupled adhesion peptides: tissue reaction.Tropism ablation and stealthing of oncolytic adenovirus enhances systemic delivery to tumors and improves virotherapy of cancer.Detection and cellular localisation of the synthetic soluble macromolecular drug carrier pHPMA.Poly(Hpma)-coated liposomes demonstrate prolonged circulation in mice.Coating of adeno-associated virus with reactive polymers can ablate virus tropism, enable retargeting and provide resistance to neutralising antisera.Passive tumour targeting of polymer-coated adenovirus for cancer gene therapy.Simultaneous delivery of doxorubicin and gemcitabine to tumors in vivo using prototypic polymeric drug carriers.Coating of vesicles with hydrophilic reactive polymers.Thermoresponsive polymers as promising new materials for local radiotherapy.Retargeting polymer-coated adenovirus to the FGF receptor allows productive infection and mediates efficacy in a peritoneal model of human ovarian cancer.Coating of DNA/poly(L-lysine) complexes by covalent attachment of poly[N-(2-hydroxypropyl)methacrylamide].Poly(ethylene glycol) multiblock copolymer as a carrier of anti-cancer drug doxorubicin.Treatment with HPMA copolymer-based doxorubicin conjugate containing human immunoglobulin induces long-lasting systemic anti-tumour immunity in mice.Decreased Binding to Proteins and Cells of Polymeric Gene Delivery Vectors Surface Modified with a Multivalent Hydrophilic Polymer and Retargeting through Attachment of TransferrinPoly[N-(2-hydroxypropyl)meth-acrylamide] Conjugates of Bovine Seminal Ribonuclease. Synthesis, Physicochemical, and Preliminary Biological EvaluationLow Temperature Aqueous Living/Controlled (RAFT) Polymerization of Carboxybetaine Methacrylamide up to High Molecular WeightsPolymeric drugs based on conjugates of synthetic and natural macromolecules. I. Synthesis and physico-chemical characterisationPolymeric drugs based on conjugates of synthetic and natural macromolecules. II. Anti-cancer activity of antibody or (Fab')(2)-targeted conjugates and combined therapy with immunomodulatorsTargeting of human and mouse T-lymphocytes by monoclonal antibody-HPMA copolymer-doxorubicin conjugates directed against different T-cell surface antigensEffect of radiotherapy and hyperthermia on the tumor accumulation of HPMA copolymer-based drug delivery systemsReactive polymers for modification of biologically active molecules and gene delivery vectorsRemovable nanocoatings for siRNA polyplexesPolymer brushes showing non-fouling in blood plasma challenge the currently accepted design of protein resistant surfacesMCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibitionSinglet oxygen phosphorescence detection in vivo identifies PDT-induced anoxia in solid tumors
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Vladimir Subr
@ast
Vladimir Subr
@en
Vladimir Subr
@es
Vladimir Subr
@nl
Vladimir Subr
@sl
type
label
Vladimir Subr
@ast
Vladimir Subr
@en
Vladimir Subr
@es
Vladimir Subr
@nl
Vladimir Subr
@sl
prefLabel
Vladimir Subr
@ast
Vladimir Subr
@en
Vladimir Subr
@es
Vladimir Subr
@nl
Vladimir Subr
@sl
P106
P1153
7004362343
P21
P31
P496
0000-0002-1614-6595