Contributions of the carboxyl-terminal helical segment to the self-association and lipoprotein preferences of human apolipoprotein E3 and E4 isoforms.
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Apolipoprotein E isoforms and lipoprotein metabolismMolecular basis for increased risk for late-onset Alzheimer disease due to the naturally occurring L28P mutation in apolipoprotein E4.Disruption of the C-terminal helix by single amino acid deletion is directly responsible for impaired cholesterol efflux ability of apolipoprotein A-I Nichinan.Influence of domain stability on the properties of human apolipoprotein E3 and E4 and mouse apolipoprotein E.Apolipoprotein E: from lipid transport to neurobiologyMass spectrometry-based protein footprinting characterizes the structures of oligomeric apolipoprotein E2, E3, and E4.Impact of self-association on function of apolipoprotein A-IHigh density lipoprotein structure-function and role in reverse cholesterol transport.Molecular mechanisms responsible for the differential effects of apoE3 and apoE4 on plasma lipoprotein-cholesterol levels.Apolipoprotein E and cholesterol in aging and disease in the brainBiophysical analysis of progressive C-terminal truncations of human apolipoprotein E4: insights into secondary structure and unfolding properties.Biophysical properties of apolipoprotein E4 variants: implications in molecular mechanisms of correction of hypertriglyceridemia.The roles of C-terminal helices of human apolipoprotein A-I in formation of high-density lipoprotein particles.Role of the N- and C-terminal domains in binding of apolipoprotein E isoforms to heparan sulfate and dermatan sulfate: a surface plasmon resonance study.Influence of N-terminal helix bundle stability on the lipid-binding properties of human apolipoprotein A-I.Biochemical and biophysical characterization of recombinant rat apolipoprotein E: similarities to human apolipoprotein E3.The extent of pyrene excimer fluorescence emission is a reflector of distance and flexibility: analysis of the segment linking the LDL receptor-binding and tetramerization domains of apolipoprotein E3.Structural differences between apolipoprotein E3 and E4 as measured by (19)F NMR.Fluorescence analysis of the lipid binding-induced conformational change of apolipoprotein E4.Interactions of apolipoprotein A-I with high-density lipoprotein particles.Molecular basis for the differences in lipid and lipoprotein binding properties of human apolipoproteins E3 and E4.Interaction between the N- and C-terminal domains modulates the stability and lipid binding of apolipoprotein A-I.Fluorescence study of domain structure and lipid interaction of human apolipoproteins E3 and E4.Helical structure, stability, and dynamics in human apolipoprotein E3 and E4 by hydrogen exchange and mass spectrometry.Molecular mechanism of apolipoprotein E binding to lipoprotein particles.The serine protease HtrA1 contributes to the formation of an extracellular 25-kDa apolipoprotein E fragment that stimulates neuritogenesis.
P2860
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P2860
Contributions of the carboxyl-terminal helical segment to the self-association and lipoprotein preferences of human apolipoprotein E3 and E4 isoforms.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Contributions of the carboxyl- ...... ipoprotein E3 and E4 isoforms.
@en
Contributions of the carboxyl- ...... ipoprotein E3 and E4 isoforms.
@nl
type
label
Contributions of the carboxyl- ...... ipoprotein E3 and E4 isoforms.
@en
Contributions of the carboxyl- ...... ipoprotein E3 and E4 isoforms.
@nl
prefLabel
Contributions of the carboxyl- ...... ipoprotein E3 and E4 isoforms.
@en
Contributions of the carboxyl- ...... ipoprotein E3 and E4 isoforms.
@nl
P2093
P2860
P356
P1433
P1476
Contributions of the carboxyl- ...... ipoprotein E3 and E4 isoforms.
@en
P2093
Charulatha Vedhachalam
David Nguyen
Hiroyuki Saito
Margaret Nickel
Masafumi Tanaka
Padmaja Dhanasekaran
Sissel Lund-Katz
Takaaki Sakamoto
P2860
P304
P356
10.1021/BI701923H
P407
P577
2008-01-18T00:00:00Z