Close correspondence between the motions from principal component analysis of multiple HIV-1 protease structures and elastic network modes.
about
Dynamics, flexibility and ligand-induced conformational changes in biological macromolecules: a computational approachChanges in dynamics upon oligomerization regulate substrate binding and allostery in amino acid kinase family membersThe use of experimental structures to model protein dynamicsElastic network models capture the motions apparent within ensembles of RNA structuresIdentifying essential pairwise interactions in elastic network model using the alpha shape theory.Distance matrix-based approach to protein structure predictionComparison of the Internal Dynamics of Metalloproteases Provides New Insights on Their Function and Evolution.The intrinsic dynamics of enzymes plays a dominant role in determining the structural changes induced upon inhibitor bindingSubstrate uptake and protein stability relationship in mammalian histidine decarboxylase.Optimal modeling of atomic fluctuations in protein crystal structures for weak crystal contact interactions.Exploring Molecular Mechanisms of Paradoxical Activation in the BRAF Kinase Dimers: Atomistic Simulations of Conformational Dynamics and Modeling of Allosteric Communication Networks and Signaling Pathways.JED: a Java Essential Dynamics Program for comparative analysis of protein trajectories.Free energies for coarse-grained proteins by integrating multibody statistical contact potentials with entropies from elastic network models.Pre-existing soft modes of motion uniquely defined by native contact topology facilitate ligand binding to proteinsAll-atom modeling of anisotropic atomic fluctuations in protein crystal structures.Iterative cluster-NMA: A tool for generating conformational transitions in proteins.Diversity of function-related conformational changes in proteins: coordinate uncertainty, fragment rigidity, and stabilityWEBnm@ v2.0: Web server and services for comparing protein flexibilityOn the conservation of the slow conformational dynamics within the amino acid kinase family: NAGK the paradigm.Computational and experimental characterization of RNA cubic nanoscaffolds.Normal mode analysis of biomolecular structures: functional mechanisms of membrane proteins.ProDy: protein dynamics inferred from theory and experiments.The mechanical properties of PCNA: implications for the loading and function of a DNA sliding clamp.MAVENs: motion analysis and visualization of elastic networks and structural ensembles.Rationale for more diverse inhibitors in competition with substrates in HIV-1 protease.Models to Approximate the Motions of Protein Loops.The landscape of the prion protein's structural response to mutation revealed by principal component analysis of multiple NMR ensemblesCoupling between catalytic loop motions and enzyme global dynamicsConformational dynamics of a regulator of G-protein signaling protein reveals a mechanism of allosteric inhibition by a small molecule.Mapping the structural and dynamical features of multiple p53 DNA binding domains: insights into loop 1 intrinsic dynamics.Dynamic Allostery Mediated by a Conserved Tryptophan in the Tec Family Kinases.Functional polyesters enable selective siRNA delivery to lung cancer over matched normal cellsMolecular determinants of cadherin ideal bond formation: Conformation-dependent unbinding on a multidimensional landscape.Structural review of PPARγ in complex with ligands: Cartesian- and dihedral angle principal component analyses of X-ray crystallographic data.iGNM 2.0: the Gaussian network model database for biomolecular structural dynamics.Simulating rare events using a weighted ensemble-based string method.Revealing an outward-facing open conformational state in a CLC Cl(-)/H(+) exchange transporterPrediction and validation of protein intermediate states from structurally rich ensembles and coarse-grained simulations.The energy profiles of atomic conformational transition intermediates of adenylate kinase.Identification of Hot Spots in Protein Structures Using Gaussian Network Model and Gaussian Naive Bayes.
P2860
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P2860
Close correspondence between the motions from principal component analysis of multiple HIV-1 protease structures and elastic network modes.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Close correspondence between t ...... res and elastic network modes.
@en
Close correspondence between t ...... res and elastic network modes.
@nl
type
label
Close correspondence between t ...... res and elastic network modes.
@en
Close correspondence between t ...... res and elastic network modes.
@nl
prefLabel
Close correspondence between t ...... res and elastic network modes.
@en
Close correspondence between t ...... res and elastic network modes.
@nl
P2093
P2860
P1433
P1476
Close correspondence between t ...... res and elastic network modes.
@en
P2093
Alicia Carriquiry
Guang Song
Robert L Jernigan
P2860
P304
P356
10.1016/J.STR.2007.12.011
P577
2008-02-01T00:00:00Z