The Delta 14 mutation of human cardiac troponin T enhances ATPase activity and alters the cooperative binding of S1-ADP to regulated actin.
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Why Is there a Limit to the Changes in Myofilament Ca2+-Sensitivity Associated with Myopathy Causing Mutations?Structural dynamics of troponin I during Ca2+-activation of cardiac thin filaments: a multi-site Förster resonance energy transfer studyThe role of cardiac troponin T quantity and function in cardiac development and dilated cardiomyopathy.Ca(2+)-regulatory function of the inhibitory peptide region of cardiac troponin I is aided by the C-terminus of cardiac troponin T: Effects of familial hypertrophic cardiomyopathy mutations cTnI R145G and cTnT R278C, alone and in combination, on filKinetics of regulated actin transitions measured by probes on tropomyosin.Facilitated cross-bridge interactions with thin filaments by familial hypertrophic cardiomyopathy mutations in α-tropomyosin.Micromechanical thermal assays of Ca2+-regulated thin-filament function and modulation by hypertrophic cardiomyopathy mutants of human cardiac troponinDetection of target ssDNA using a microfabricated Hall magnetometer with correlated optical readout.The C-terminus of troponin T is essential for maintaining the inactive state of regulated actinNegative charges at protein kinase C sites of troponin I stabilize the inactive state of actinStructures of the troponin core domain containing the cardiomyopathy-causing mutants studied by small-angle X-ray scattering.Slowed Dynamics of Thin Filament Regulatory Units Reduces Ca(2+)-Sensitivity of Cardiac Biomechanical Function.Cardiac muscle activation blunted by a mutation to the regulatory component, troponin TA computational and experimental approach to investigate bepridil binding with cardiac troponin.Molecular dynamics studies on troponin (TnI-TnT-TnC) complexes: insight into the regulation of muscle contraction.Some cardiomyopathy-causing troponin I mutations stabilize a functional intermediate actin state.Disease causing mutations of troponin alter regulated actin state distributions.Nuclear tropomyosin and troponin in striated muscle: new roles in a new locale?Commentary: Effect of Skeletal Muscle Native Tropomyosin on the Interaction of Amoeba Actin with Heavy Meromyosin.Several cardiomyopathy causing mutations on tropomyosin either destabilize the active state of actomyosin or alter the binding properties of tropomyosin.
P2860
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P2860
The Delta 14 mutation of human cardiac troponin T enhances ATPase activity and alters the cooperative binding of S1-ADP to regulated actin.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
The Delta 14 mutation of human ...... of S1-ADP to regulated actin.
@en
The Delta 14 mutation of human ...... of S1-ADP to regulated actin.
@nl
type
label
The Delta 14 mutation of human ...... of S1-ADP to regulated actin.
@en
The Delta 14 mutation of human ...... of S1-ADP to regulated actin.
@nl
prefLabel
The Delta 14 mutation of human ...... of S1-ADP to regulated actin.
@en
The Delta 14 mutation of human ...... of S1-ADP to regulated actin.
@nl
P2093
P2860
P356
P1433
P1476
The Delta 14 mutation of human ...... g of S1-ADP to regulated actin
@en
P2093
Bernhard Brenner
Boris Gafurov
Scott Fredricksen
P2860
P304
15276-15285
P356
10.1021/BI048646H
P407
P577
2004-12-01T00:00:00Z