Reciprocal regulation of the Ca2+ and H+ sensitivity in the SLO1 BK channel conferred by the RCK1 domain.
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Structure of the human BK channel Ca2+-activation apparatus at 3.0 A resolutionStructure of the gating ring from the human large-conductance Ca(2+)-gated K(+) channelBK channels: multiple sensors, one activation gateFunction and regulation of large conductance Ca(2+)-activated K+ channel in vascular smooth muscle cellsCrystal Structure of a Ba2+-Bound Gating Ring Reveals Elementary Steps in RCK Domain ActivationStructural basis of allosteric interactions among Ca2+-binding sites in a K+ channel RCK domainHuman EAG channels are directly modulated by PIP2 as revealed by electrophysiological and optical interference investigationsA review on hemeoxygenase-2: focus on cellular protection and oxygen responseA heme-binding domain controls regulation of ATP-dependent potassium channels.Alcohol withdrawal is associated with a downregulation of large-conductance Ca²⁺-activated K⁺ channels in rat inferior colliculus neurons.Zn2+ activates large conductance Ca2+-activated K+ channel via an intracellular domain.Carbon monoxide--physiology, detection and controlled release.Identification of a thiol/disulfide redox switch in the human BK channel that controls its affinity for heme and COThe RCK1 domain of the human BKCa channel transduces Ca2+ binding into structural rearrangementsBK channel activation: structural and functional insightsThiol/Disulfide redox switches in the regulation of heme binding to proteins.Metal-driven operation of the human large-conductance voltage- and Ca2+-dependent potassium channel (BK) gating ring apparatus.Charge substitution for a deep-pore residue reveals structural dynamics during BK channel gating.Single Channel Recordings Reveal Differential β2 Subunit Modulations Between Mammalian and Drosophila BKCa(β2) Channels.Mechanism of the modulation of BK potassium channel complexes with different auxiliary subunit compositions by the omega-3 fatty acid DHA.Omega-3 fatty acids lower blood pressure by directly activating large-conductance Ca²⁺-dependent K⁺ channels.Activation of Slo1 BK channels by Mg2+ coordinated between the voltage sensor and RCK1 domains.Block of mouse Slo1 and Slo3 K+ channels by CTX, IbTX, TEA, 4-AP and quinidine.Transduction of voltage and Ca2+ signals by Slo1 BK channels.Molecular mechanisms of BK channel activation.Properties of Slo1 K+ channels with and without the gating ring.Modulation of BKCa channel gating by endogenous signaling molecules.Atomic determinants of BK channel activation by polyunsaturated fatty acids.The Ca2+-activated K+ current of human sperm is mediated by Slo3.Targeting BK (big potassium) channels in epilepsy.Potassium channels: structures, diseases, and modulators.BKCa channel dysfunction in neurological diseasesMechanistic insight into the heme-independent interplay between iron and carbon monoxide in CFTR and Slo1 BKCa channels.Understanding the conformational motions of RCK gating rings.Comparative effects of H+ and Ca2+ on large-conductance Ca2+- and voltage-gated Slo1 K+ channels.CO-independent modification of K+ channels by tricarbonyldichlororuthenium(II) dimer (CORM-2).BK channel inhibition by strong extracellular acidification
P2860
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P2860
Reciprocal regulation of the Ca2+ and H+ sensitivity in the SLO1 BK channel conferred by the RCK1 domain.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Reciprocal regulation of the C ...... conferred by the RCK1 domain.
@en
Reciprocal regulation of the C ...... conferred by the RCK1 domain.
@nl
type
label
Reciprocal regulation of the C ...... conferred by the RCK1 domain.
@en
Reciprocal regulation of the C ...... conferred by the RCK1 domain.
@nl
prefLabel
Reciprocal regulation of the C ...... conferred by the RCK1 domain.
@en
Reciprocal regulation of the C ...... conferred by the RCK1 domain.
@nl
P2093
P2860
P356
P1476
Reciprocal regulation of the C ...... conferred by the RCK1 domain.
@en
P2093
Shangwei Hou
Toshinori Hoshi
P2860
P2888
P304
P356
10.1038/NSMB.1398
P577
2008-03-16T00:00:00Z
P5875
P6179
1015200029