AP1 factor inactivation in the suprabasal epidermis causes increased epidermal hyperproliferation and hyperkeratosis but reduced carcinogen-dependent tumor formation
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Suppression of AP1 transcription factor function in keratinocyte suppresses differentiationDifferentiation-associated genes regulated by c-Jun and decreased in the progression of esophageal squamous cell carcinoma.Suppressing AP1 factor signaling in the suprabasal epidermis produces a keratoderma phenotype.Dissecting the psoriasis transcriptome: inflammatory- and cytokine-driven gene expression in lesions from 163 patientsc-Jun promotes whereas JunB inhibits epidermal neoplasiaPerturbation of BRD4 protein function by BRD4-NUT protein abrogates cellular differentiation in NUT midline carcinomaProtein kinase C (PKC) delta suppresses keratinocyte proliferation by increasing p21(Cip1) level by a KLF4 transcription factor-dependent mechanism.Methylosome Protein 50 and PKCδ/p38δ Protein Signaling Control Keratinocyte Proliferation via Opposing Effects on p21Cip1 Gene ExpressionStructural and biochemical changes underlying a keratoderma-like phenotype in mice lacking suprabasal AP1 transcription factor function.Modeling cutaneous squamous carcinoma development in the mouseMechanism of interleukin-1β-induced proliferation in rat hepatic stellate cells from different levels of signal transduction.Loss of epidermal AP1 transcription factor function reduces filaggrin level, alters chemokine expression and produces an ichthyosis-related phenotype.Embryonic AP1 Transcription Factor Deficiency Causes a Collodion Baby-Like PhenotypeAP1 transcription factors in epidermal differentiation and skin cancerCrucial role of c-Jun phosphorylation at Ser63/73 mediated by PHLPP protein degradation in the cheliensisin a inhibition of cell transformation.MEP50/PRMT5 Reduces Gene Expression by Histone Arginine Methylation and this Is Reversed by PKCδ/p38δ Signaling.PKCη promotes a proliferation to differentiation switch in keratinocytes via upregulation of p27Kip1 mRNA through suppression of JNK/c-Jun signaling under stress conditions.Insights into gene expression profiles induced by Socs3 depletion in keratinocytes.
P2860
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P2860
AP1 factor inactivation in the suprabasal epidermis causes increased epidermal hyperproliferation and hyperkeratosis but reduced carcinogen-dependent tumor formation
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
AP1 factor inactivation in the ...... ogen-dependent tumor formation
@en
AP1 factor inactivation in the ...... ogen-dependent tumor formation
@nl
type
label
AP1 factor inactivation in the ...... ogen-dependent tumor formation
@en
AP1 factor inactivation in the ...... ogen-dependent tumor formation
@nl
prefLabel
AP1 factor inactivation in the ...... ogen-dependent tumor formation
@en
AP1 factor inactivation in the ...... ogen-dependent tumor formation
@nl
P2093
P2860
P356
P1433
P1476
AP1 factor inactivation in the ...... ogen-dependent tumor formation
@en
P2093
P2860
P2888
P304
P356
10.1038/ONC.2010.315
P407
P577
2010-09-06T00:00:00Z
P5875
P6179
1018136074