about
The relationship between amyloid structure and cytotoxicityThe strain-encoded relationship between PrP replication, stability and processing in neurons is predictive of the incubation period of diseaseAtomic View of a Toxic Amyloid Small OligomerMeasurement of amyloid formation by turbidity assay-seeing through the cloudA multiscale approach to characterize the early aggregation steps of the amyloid-forming peptide GNNQQNY from the yeast prion sup-35Resveratrol acts not through anti-aggregative pathways but mainly via its scavenging properties against Aβ and Aβ-metal complexes toxicityInter-species cross-seeding: stability and assembly of rat-human amylin aggregatesβ2-Microglobulin amyloid fibril-induced membrane disruption is enhanced by endosomal lipids and acidic pHComparison of the aggregation of homologous β2-microglobulin variants reveals protein solubility as a key determinant of amyloid formationThe binding of apolipoprotein E to oligomers and fibrils of amyloid-β alters the kinetics of amyloid aggregation.Enhanced Fibril Fragmentation of N-Terminally Truncated and Pyroglutamyl-Modified Aβ Peptides.Mechanistic and environmental control of the prevalence and lifetime of amyloid oligomersAmyloid β-Protein C-Terminal Fragments: Formation of Cylindrins and β-Barrels.The assembly of individual chaplin peptides from Streptomyces coelicolor into functional amyloid fibrils.Designed Trpzip-3 β-Hairpin Inhibits Amyloid Formation in Two Different Amyloid SystemsAmyloid-like aggregates of the yeast prion protein ure2 enter vertebrate cells by specific endocytotic pathways and induce apoptosis.Designed α-sheet peptides inhibit amyloid formation by targeting toxic oligomers.Stacked sets of parallel, in-register beta-strands of beta2-microglobulin in amyloid fibrils revealed by site-directed spin labeling and chemical labeling.A molecular dynamics study of the early stages of amyloid-beta(1-42) oligomerization: the role of lipid membranes.A yeast toxic mutant of HET-s((218-289)) prion displays alternative intermediates of amyloidogenesisInteraction between human prion protein and amyloid-beta (Abeta) oligomers: role OF N-terminal residues.Characterization of the response of primary cells relevant to dialysis-related amyloidosis to β2-microglobulin monomer and fibrils.An equilibrium model for linear and closed-loop amyloid fibril formation.The tempered polymerization of human neuroserpin.Amyloid fibrils composed of hexameric peptides attenuate neuroinflammation.Direct three-dimensional visualization of membrane disruption by amyloid fibrilsThe relationship between aggregation and toxicity of polyglutamine-containing ataxin-3 in the intracellular environment of Escherichia coli.Mechanism of amylin fibrillization enhancement by heparin.Amyloid aggregation and deposition of human islet amyloid polypeptide at membrane interfaces.Nanomechanics and intermolecular forces of amyloid revealed by four-dimensional electron microscopy.A kinetic study of ovalbumin fibril formation: the importance of fragmentation and end-joiningAmyloid polymorphism: structural basis and neurobiological relevance.Soluble Aβ seeds are potent inducers of cerebral β-amyloid depositionpH-induced molecular shedding drives the formation of amyloid fibril-derived oligomersThe toxicity of an "artificial" amyloid is related to how it interacts with membranes.Effect of sequence variation on the mechanical response of amyloid fibrils probed by steered molecular dynamics simulationEndocytosed 2-Microglobulin Amyloid Fibrils Induce Necrosis and Apoptosis of Rabbit Synovial Fibroblasts by Disrupting Endosomal/Lysosomal Membranes: A Novel Mechanism on the Cytotoxicity of Amyloid Fibrils.Bayesian graphical network analyses reveal complex biological interactions specific to Alzheimer's diseaseDissecting the kinetic process of amyloid fiber formation through asymptotic analysis.Membrane-mediated amyloid formation of PrP 106-126: A kinetic study.
P2860
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P2860
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Fibril fragmentation enhances amyloid cytotoxicity.
@en
Fibril fragmentation enhances amyloid cytotoxicity.
@en-gb
Fibril fragmentation enhances amyloid cytotoxicity.
@nl
type
label
Fibril fragmentation enhances amyloid cytotoxicity.
@en
Fibril fragmentation enhances amyloid cytotoxicity.
@en-gb
Fibril fragmentation enhances amyloid cytotoxicity.
@nl
prefLabel
Fibril fragmentation enhances amyloid cytotoxicity.
@en
Fibril fragmentation enhances amyloid cytotoxicity.
@en-gb
Fibril fragmentation enhances amyloid cytotoxicity.
@nl
P2860
P50
P356
P1476
Fibril fragmentation enhances amyloid cytotoxicity.
@en
P2093
Steve W Homans
Walraj S Gosal
P2860
P304
34272-34282
P356
10.1074/JBC.M109.049809
P407
P577
2009-10-06T00:00:00Z