TSC loss distorts DNA replication programme and sensitises cells to genotoxic stress

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Heterozygous loss of TSC2 alters p53 signaling and human stem cell reprogramming.

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Q49650210-19783CB4-3CDA-4984-9C25-1E79E467AD0E

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TSC loss distorts DNA replication programme and sensitises cells to genotoxic stress

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2016 nî lūn-bûn

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年论文

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2016年论文

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TSC loss distorts DNA replication programme and sensitises cells to genotoxic stress

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TSC loss distorts DNA replication programme and sensitises cells to genotoxic stress

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TSC loss distorts DNA replication programme and sensitises cells to genotoxic stress

@en

TSC loss distorts DNA replication programme and sensitises cells to genotoxic stress

@nl

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TSC loss distorts DNA replication programme and sensitises cells to genotoxic stress

@en

TSC loss distorts DNA replication programme and sensitises cells to genotoxic stress

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P1476

TSC loss distorts DNA replication programme and sensitises cells to genotoxic stress

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Alexandra Zielinski

http://www.w3.org/2001/XMLSchema#string

Govind M Pai

http://www.w3.org/2001/XMLSchema#string

Helmut Pospiech

http://www.w3.org/2001/XMLSchema#string

Ignacio Rubio

http://www.w3.org/2001/XMLSchema#string

Kerstin Borgmann

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Kristin Ludwig

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Zhao-Qi Wang

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The Hallmarks of Cancer

Hallmarks of Cancer: The Next Generation

The TSC1 gene product, hamartin, negatively regulates cell proliferation

mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E

mTOR signaling in growth control and disease

AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function

Glutamine and cancer: cell biology, physiology, and clinical opportunities

Regulation of mTORC1 by amino acids

TSC2 mediates cellular energy response to control cell growth and survival

p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling

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85365-85380

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scholarly article

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10.18632/ONCOTARGET.13378

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English

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http://www.w3.org/2001/XMLSchema#string

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http://www.w3.org/2001/XMLSchema#string

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Dennis Koalick

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2016-11-16T00:00:00Z

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27863419

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5356742

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TSC loss distorts DNA replication programme and sensitises cells to genotoxic stress

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P2860

P2860

TSC loss distorts DNA replication programme and sensitises cells to genotoxic stress

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P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932