Autoimmune disorders associated with gain of function of the intracellular sensor MDA5.
about
Dysregulation of antiviral helicase pathways in systemic lupus erythematosusTargeted therapeutics in SLE: emerging strategies to modulate the interferon pathwayRegulation of antiviral innate immune signaling by stress-induced RNA granulesMDA5-positive dermatomyositis: an uncommon entity in Europe with variable clinical presentationsLinking susceptibility genes and pathogenesis mechanisms using mouse models of systemic lupus erythematosusThe Role of Damage-Associated Molecular Patterns in Human Diseases: Part I - Promoting inflammation and immunityMDA5 and LGP2: accomplices and antagonists of antiviral signal transductionThe enemy within: endogenous retroelements and autoimmune diseaseHuman β-Defensin 3 [corrected] Exacerbates MDA5 but Suppresses TLR3 Responses to the Viral Molecular Pattern Mimic Polyinosinic:Polycytidylic AcidInternational Union of Basic and Clinical Pharmacology. XCVI. Pattern recognition receptors in health and diseaseLGP2 synergy with MDA5 in RLR-mediated RNA recognition and antiviral signalingAn image-based genetic assay identifies genes in T1D susceptibility loci controlling cellular antiviral immunity in mouseMutations in DDX58, which encodes RIG-I, cause atypical Singleton-Merten syndrome.A Critical Role for the Type I Interferon Receptor in Virus-Induced Autoimmune Diabetes in Rats.Lupus pathobiology based on genomics.MAVS is not a Likely Susceptibility Locus for Addison's Disease and Type 1 Diabetes.Aicardi-Goutières syndrome is caused by IFIH1 mutations.A specific IFIH1 gain-of-function mutation causes Singleton-Merten syndrome.Aicardi-Goutières syndrome and the type I interferonopathies.Negative regulation of melanoma differentiation-associated gene 5 (MDA5)-dependent antiviral innate immune responses by Arf-like protein 5BInterferon regulatory factors: critical mediators of human lupus.Immunological loss-of-function due to genetic gain-of-function in humans: autosomal dominance of the third kindHigh Affinity Antibodies against Influenza Characterize the Plasmablast Response in SLE Patients After Vaccination.Kinetic discrimination of self/non-self RNA by the ATPase activity of RIG-I and MDA5MDA5-filament, dynamics and disease.Antiviral Protection via RdRP-Mediated Stable Activation of Innate Immunity.The RNA-editing enzyme ADAR1 controls innate immune responses to RNA.Association of IFIH1 and pro-inflammatory mediators: Potential new clues in SLE-associated pathogenesis.GPATCH3 negatively regulates RLR-mediated innate antiviral responses by disrupting the assembly of VISA signalosomeATP hydrolysis by the viral RNA sensor RIG-I prevents unintentional recognition of self-RNA.The autoinhibitory CARD2-Hel2i Interface of RIG-I governs RNA selection.Primary Immunodeficiencies and Inflammatory Disease: A Growing Genetic Intersection.Immunoinflammatory diseases of the central nervous system - the tale of two cytokines.Unusual cutaneous features associated with a heterozygous gain-of-function mutation in IFIH1: overlap between Aicardi-Goutières and Singleton-Merten syndromes.Autoimmunity in picornavirus infections.Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5Type I interferon-mediated monogenic autoinflammation: The type I interferonopathies, a conceptual overviewWhen your cap matters: structural insights into self vs non-self recognition of 5' RNA by immunomodulatory host proteins.Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling.Antiviral RNA recognition and assembly by RLR family innate immune sensors.
P2860
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P2860
Autoimmune disorders associated with gain of function of the intracellular sensor MDA5.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Autoimmune disorders associated with gain of function of the intracellular sensor MDA5.
@en
Autoimmune disorders associated with gain of function of the intracellular sensor MDA5.
@nl
type
label
Autoimmune disorders associated with gain of function of the intracellular sensor MDA5.
@en
Autoimmune disorders associated with gain of function of the intracellular sensor MDA5.
@nl
prefLabel
Autoimmune disorders associated with gain of function of the intracellular sensor MDA5.
@en
Autoimmune disorders associated with gain of function of the intracellular sensor MDA5.
@nl
P2093
P1433
P1476
Autoimmune disorders associated with gain of function of the intracellular sensor MDA5
@en
P2093
Aiko Yoshida
Hideaki Toki
Hiroki Kato
Hiromi Motegi
Hiroshi Sato
Katashi Deguchi
Kunio Takeyasu
Maki Inoue
Masahide Funabiki
Osamu Minowa
P304
P356
10.1016/J.IMMUNI.2013.12.014
P407
P577
2014-02-13T00:00:00Z